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免疫应答在感染性疾病中的性别差异。

Sex differences in immune responses to infectious diseases.

机构信息

First Department of Internal Medicine, University of Cologne, Kerpener Str. 62, 50934, Cologne, Germany.

出版信息

Infection. 2015 Aug;43(4):399-403. doi: 10.1007/s15010-015-0791-9. Epub 2015 May 9.

Abstract

PURPOSE

The influence of sex hormones is recognized to account for the susceptibility and distinct outcomes of diverse infectious diseases.

METHODS

This review discusses several variables including differences in behavior and exposure to pathogens, genetic, and immunological factors.

CONCLUSION

Understanding sex-based differences in immunity during different infectious diseases is crucial in order to provide optimal disease management for both sexes.

摘要

目的

性激素的影响被认为是导致多种传染病易感性和不同结局的原因。

方法

本文讨论了几个变量,包括行为和病原体暴露的差异、遗传和免疫因素。

结论

了解不同传染病期间基于性别的免疫差异对于为两性提供最佳疾病管理至关重要。

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