Skogvoll E, Hoel T M, Smith-Erichsen N, Melsom R
Tidsskr Nor Laegeforen. 1989 Nov 20;109(32):3323-5.
We describe five cases of anaphylactic shock following the short-acting muscle relaxant succinylcholine (suxamethonium). All the patients recovered uneventfully. Skin prick testing identified succinylcholine as the probable causative agent in four cases. The incidence of anaphylaxis to succinylcholine in our material appears to be 1:1,000. Treatment consisted of volume substitution, adequate oxygenation and adrenergic agents. We discuss the routine use of succinylcholine for intubation in elective surgery, and conclude that the anaesthesiologist must always be prepared for a possible anaphylactic reaction.
我们描述了5例使用短效肌肉松弛剂琥珀酰胆碱(司可林)后发生过敏性休克的病例。所有患者均顺利康复。皮肤点刺试验确定4例案例中琥珀酰胆碱可能是致病因素。在我们的病例资料中,对琥珀酰胆碱过敏反应的发生率似乎为1:1000。治疗包括容量补充、充分给氧和使用肾上腺素能药物。我们讨论了在择期手术中常规使用琥珀酰胆碱进行插管的情况,并得出结论,麻醉医生必须始终为可能发生的过敏反应做好准备。