Turcios Silvia, Lence-Anta Juan J, Santana Jose-Luis, Pereda Celia M, Velasco Milagros, Chappe Mae, Infante Idalmis, Bustillo Marlene, García Anabel, Clero Enora, Maillard Stephane, Rodriguez Regla, Xhaard Constance, Ren Yan, Rubino Carole, Ortiz Rosa M, de Vathaire Florent
National Institute of Endocrinology, Havana, Cuba.
Institute of Oncology and Radiobiology, Havana, Cuba.
Eur Thyroid J. 2015 Mar;4(1):55-61. doi: 10.1159/000371346. Epub 2015 Feb 26.
The aim of this study was to describe the thyroid volume in healthy adults by ultrasound and to correlate this volume with some anthropometric measures and other differentiated thyroid cancer risk factors.
Thyroid volume and anthropometric measures were recorded in a sample of 100 healthy adults, including 21 men and 79 women aged 18-50 years, living in a non-iodine-deficient area of Havana city.
The average thyroid volume was 6.6 ± 0.26 ml; it was higher in men (7.3 ml) than in women (6.4 ml; p = 0.15). In the univariate analysis, thyroid volume was correlated with all anthropometric measures, but in the multivariate analysis, body surface area was found to be the only significant anthropometric parameter. Thyroid volume was also higher in current or former smokers and in persons with blood group AB or B.
Specific reference values of thyroid volume as a function of body surface area could be used for evaluating thyroid volume in clinical practice. The relation between body surface area and thyroid volume is coherent with what is known about the relation of thyroid volume to thyroid cancer risk, but the same is not true about the relation between thyroid volume and smoking habit.
本研究旨在通过超声描述健康成年人的甲状腺体积,并将该体积与一些人体测量指标及其他分化型甲状腺癌风险因素进行关联。
对100名健康成年人进行了甲状腺体积和人体测量指标记录,这些成年人包括21名男性和79名女性,年龄在18至50岁之间,居住在哈瓦那市非碘缺乏地区。
平均甲状腺体积为6.6±0.26毫升;男性(7.3毫升)高于女性(6.4毫升;p = 0.15)。在单因素分析中,甲状腺体积与所有人体测量指标相关,但在多因素分析中,发现体表面积是唯一显著的人体测量参数。当前或既往吸烟者以及AB型或B型血的人的甲状腺体积也较高。
作为体表面积函数的甲状腺体积特定参考值可用于临床实践中评估甲状腺体积。体表面积与甲状腺体积之间的关系与已知的甲状腺体积与甲状腺癌风险的关系一致,但甲状腺体积与吸烟习惯之间的关系并非如此。