Uhart M, Blein C, L'Azou M, Thomas L, Durand L
Global Health Sanofi Pasteur, Lyon, 69007, France.
Health Economist, HEVA, 186 Avenue Thiers, 69465 Lyon Cedex 06, France.
Eur J Health Econ. 2016 May;17(4):497-503. doi: 10.1007/s10198-015-0694-9. Epub 2015 May 12.
Dengue is a major emerging public health concern in tropical and subtropical countries. Severe dengue can lead to hospitalisation and death. This study was performed to assess the economic burden of hospitalisations for dengue from 2007 to 2011 in three French territories of the Americas where dengue is endemic (French Guiana, Martinique and Guadeloupe).
Data on dengue-associated hospitalisations were extracted from the French national hospital administrative database, Programme de Médicalisation des Systèmes d'Information (PMSI). The numbers of stays and the corresponding number of hospitalised patients were determined using disease-specific ICD-10 codes. Associated hospital costs were estimated from the payer perspective, using French official tariffs.
Overall, 4183 patients (mean age 32 years; 51 % male) were hospitalised for dengue, corresponding to 4574 hospital stays. In nearly all hospital stays (98 %; 4471), the illness was medically managed and the mean length of stay was 4.3 days. The mean cost per stay was €2522, corresponding to a total hospital cost of €11.5 million over the 5 years assessed. The majority of hospitalisations (80 % of patients) and associated costs (75 % of total hospital costs) were incurred during two epidemics.
Severe dengue is associated with significant hospital costs that escalate during outbreaks.
登革热是热带和亚热带国家主要的新出现的公共卫生问题。严重登革热可导致住院和死亡。本研究旨在评估2007年至2011年期间,在美洲的三个登革热流行的法国属地(法属圭亚那、马提尼克岛和瓜德罗普岛)登革热住院的经济负担。
登革热相关住院数据从法国国家医院管理数据库“信息系统医疗化计划”(PMSI)中提取。使用特定疾病的ICD-10编码确定住院次数和相应的住院患者数量。从支付方角度,使用法国官方收费标准估算相关住院费用。
总体而言,4183名患者(平均年龄32岁;51%为男性)因登革热住院,相当于4574次住院。几乎所有住院(98%;4471次)都进行了医疗处理,平均住院时间为4.3天。每次住院的平均费用为2522欧元,在评估的5年期间,住院总费用为1150万欧元。大多数住院(80%的患者)和相关费用(占住院总费用的75%)发生在两次疫情期间。
严重登革热与高额住院费用相关,疫情期间费用会增加。