视网膜光照度降低对自动视野阈值测量的影响。

The influence of decreased retinal illumination on automated perimetric threshold measurements.

作者信息

Heuer D K, Anderson D R, Feuer W J, Gressel M G

机构信息

Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles.

出版信息

Am J Ophthalmol. 1989 Dec 15;108(6):643-50. doi: 10.1016/0002-9394(89)90855-6.

DOI:10.1016/0002-9394(89)90855-6

PMID:2596543

Abstract

Decreased retinal illumination (such as can be caused by pupillary constriction or light absorption by ocular media opacities) was simulated with a randomly ordered series of neutral density filters in front of the right eyes of five subjects with dilated pupils. Threshold measurements were performed on Humphrey and Octopus perimeters at 0, 5, 10, 15, 20, and 25 degrees nasally along the 180-degree meridian. A 0.6-log unit neutral density filter, which reduces retinal illumination the equivalent of halving the pupillary diameter, decreased the mean Humphrey thresholds by 1.1 +/- 0.8 decibels (dB) (mean +/- standard deviation) and the mean Octopus thresholds by 1.7 +/- 1.4 dB. Statistically significant (P less than or equal to .05, Dunnett's test) threshold depressions were observed at all eccentricities with a 1.5-log unit neutral density filter on the Humphrey perimeter (-4.5 +/- 0.7 dB) and with a 1.0-log unit neutral density filter on the Octopus perimeter (-3.5 +/- 1.0 dB).

摘要

在五名瞳孔散大的受试者右眼前方，使用一系列随机排列的中性密度滤光片模拟视网膜光照度降低（如可由瞳孔收缩或眼介质混浊对光的吸收引起）。沿着180度子午线在鼻侧0、5、10、15、20和25度处，使用Humphrey视野计和Octopus视野计进行阈值测量。一个0.6对数单位的中性密度滤光片，其降低视网膜光照度的效果等同于将瞳孔直径减半，使Humphrey视野计的平均阈值降低了1.1±0.8分贝（dB）（平均值±标准差），使Octopus视野计的平均阈值降低了1.7±1.4分贝。在Humphrey视野计上使用1.5对数单位的中性密度滤光片（-4.5±0.7分贝）以及在Octopus视野计上使用1.0对数单位的中性密度滤光片（-3.5±1.0分贝）时，在所有偏心度处均观察到具有统计学意义（P≤0.05，Dunnett检验）的阈值降低。