Kelleher M B, Iwatsuki S, Sheahan D G
Department of Pathology, Presbyterian-University Hospital, Pittsburgh, Pennsylvania 15213.
Am J Surg Pathol. 1989 Dec;13(12):999-1008. doi: 10.1097/00000478-198912000-00001.
We present a review of the clinicopathologic features of a series of 10 patients with hepatic epithelioid hemangioendothelioma treated by orthotopic liver transplantation. This tumor has an unpredictable prognosis. Morphological features predictive of biological behavior were not identified in these patients. It appears that metastatic spread at the time of surgery is not a significant contraindication to surgery and has no correlation with survival. Nine patients are alive (5-134 months), five disease free and four with tumor. The etiology of this tumor is unknown. However, there is an association of oral contraceptive use with this tumor in four (66%) of the six female patients in this series and in 37% of such reported cases.
我们对10例接受原位肝移植治疗的肝上皮样血管内皮瘤患者的临床病理特征进行了综述。该肿瘤预后不可预测。在这些患者中未发现可预测生物学行为的形态学特征。似乎手术时的转移扩散并非手术的重大禁忌证，且与生存率无关。9例患者存活（5 - 134个月），5例无疾病，4例有肿瘤。该肿瘤的病因不明。然而，在本系列6例女性患者中的4例（66%）以及37%的此类报道病例中，口服避孕药的使用与该肿瘤有关联。
