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纳米颗粒在毛细管电泳中的分析与应用

Analysis and applications of nanoparticles in capillary electrophoresis.

作者信息

Ban Eunmi, Yoo Young Sook, Song Eun Joo

机构信息

Molecular Recognition Research Center, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea; Advanced Institutes of Convergence Technology, BioInfra Co., Ltd., Gyunggi-do 443-270, Republic of Korea.

Molecular Recognition Research Center, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea.

出版信息

Talanta. 2015 Aug 15;141:15-20. doi: 10.1016/j.talanta.2015.03.020. Epub 2015 Apr 1.

Abstract

Nanoparticles (NPs) exhibit unique chemical and physical properties that depend on their size, shape, and environment. NPs are emerging as new tools and techniques in the analytical study of various materials and in the biological and biomedical fields, because of their unique properties. Therefore, the quantitative and qualitative characterization of NPs has gathered increasing interest. Additionally, the NPs are being used in rapidly developing techniques to provide highly sensitive and specific analysis of various materials. Capillary electrophoresis (CE) has been demonstrated as a useful analytical tool for the characterization of NPs and for the evaluation of biological and biomedical studies using NPs because of its simple sample preparation and efficient resolution of a diverse size range of compounds. This paper gives a short overview of the analysis and applications of NPs in CE systems, with an emphasis on biological and biomedical studies.

摘要

纳米颗粒(NPs)具有取决于其尺寸、形状和环境的独特化学和物理性质。由于其独特的性质,纳米颗粒正在成为各种材料分析研究以及生物和生物医学领域中的新工具和技术。因此,纳米颗粒的定量和定性表征越来越受到关注。此外,纳米颗粒正被用于快速发展的技术中,以对各种材料进行高度灵敏和特异的分析。毛细管电泳(CE)已被证明是一种用于纳米颗粒表征以及评估使用纳米颗粒的生物和生物医学研究的有用分析工具,因为其样品制备简单且能有效分离各种大小范围的化合物。本文简要概述了纳米颗粒在毛细管电泳系统中的分析和应用,重点是生物和生物医学研究。

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