Tanindi Asli, Ugurlu Murat, Tore Hasan Fehmi
Department of Cardiology, Ufuk University Faculty of Medicine , Ankara , Turkey.
Scand Cardiovasc J. 2015 Aug;49(4):220-7. doi: 10.3109/14017431.2015.1045934. Epub 2015 May 15.
We investigated blood pressure (BP) response to exercise with respect to BP morning surge (MS), and the association between MS, exercise treadmill test (ETT) and heart rate variability (HRV) indices.
Eighty-four healthy subjects without hypertension were enrolled. Ambulatory BP monitoring and 24-hour Holter recordings were obtained for sleep-trough MS and HRV indices: low-frequency (LF) component, high-frequency (HF) component and LF/HF ratio. ETT was performed, and BPs were obtained at rest, end of each stage, and recovery. Third-minute heart rate recovery (HRR) and BP recovery ratio (BPRR) were calculated.
When analysed in quartiles of MS, systolic BP at low workloads was higher in the highest than in the lowest quartile, although maximum BPs at maximum exercise were not significantly different. BPRR was highest in the highest quartile in contrast to HRR, which was lowest in the highest quartile. LF/HF was highest during both at daytime and night-time in the highest quartile. BPRR and LF/HF were positively, and HRR was inversely associated with MS.
Subjects with a high MS have higher BP at low workloads, at which most daily activities are performed, and impairment in some indices, which indirectly reflect the autonomic nervous system.
我们研究了运动时血压（BP）对血压晨峰（MS）的反应，以及MS、运动平板试验（ETT）和心率变异性（HRV）指标之间的关联。
纳入84名无高血压的健康受试者。通过动态血压监测和24小时动态心电图记录获取睡眠低谷时的MS和HRV指标：低频（LF）成分、高频（HF）成分和LF/HF比值。进行ETT，并在静息、每个阶段结束时和恢复阶段测量血压。计算第3分钟心率恢复（HRR）和血压恢复率（BPRR）。
按MS四分位数分析时，尽管最大运动时的最高血压无显著差异，但最高四分位数组在低负荷运动时的收缩压高于最低四分位数组。与HRR相反，BPRR在最高四分位数组中最高，而HRR在最高四分位数组中最低。最高四分位数组在白天和夜间的LF/HF均最高。BPRR和LF/HF与MS呈正相关，而HRR与MS呈负相关。
MS较高的受试者在低负荷运动时血压较高，而大多数日常活动都是在低负荷运动时进行的，并且某些指标出现异常，这些指标间接反映了自主神经系统。
