Mader S L
Department of Medicine, Case Western Reserve University, Cleveland, Ohio.
Arch Intern Med. 1989 Dec;149(12):2757-60.
Previous data suggest that postural and postprandial hypotension are common in elderly subjects. This study evaluated the effect of age, meals, and time of day on supine and standing blood pressure (BP) and heart rate in healthy young and elderly subjects. A postural BP protocol was performed on 10 young and 16 elderly subjects during an overnight stay. The protocol included first morning and postprandial readings. The systolic and diastolic BP responses to standing were not significantly different between the two groups and were not affected by time of day. Postprandial recumbent BPs declined significantly only in the older subjects. There was no effect of meals on the BP response to standing. We conclude that healthy elderly subjects have a postprandial decline in BP even when supine. However, the BP response to standing is similar in young and elderly subjects and is not impaired by overnight rest or meals. This suggests that the regulation of BP after meals and with standing may be different.
先前的数据表明，体位性低血压和餐后低血压在老年人群中很常见。本研究评估了年龄、进餐情况和一天中的时间对健康年轻和老年受试者仰卧位和站立位血压（BP）及心率的影响。对10名年轻受试者和16名老年受试者在过夜期间进行了体位性血压检测方案。该方案包括首次晨测和餐后测量。两组受试者站立时的收缩压和舒张压反应无显著差异，且不受一天中时间的影响。仅老年受试者的餐后卧位血压显著下降。进餐对站立时的血压反应没有影响。我们得出结论，即使在仰卧位时，健康老年受试者的血压在餐后也会下降。然而，年轻和老年受试者站立时的血压反应相似，且不受过夜休息或进餐的影响。这表明餐后和站立时血压的调节可能有所不同。
