以急性肝衰竭为表现的小细胞肺癌弥漫性肝转移经颈静脉肝活检确诊：1例经增强CT检查发现结节性病变的罕见病例
Diffuse Liver Metastasis of Small-Cell Lung Cancer Presenting as Acute Liver Failure and Diagnosed by Transjugular Liver Biopsy: A Rare Case in Whom Nodular Lesions Were Detected by Enhanced CT Examination.
作者信息
Mishima S, Nozaki Y, Mikami S, Kihira E, Iikura M, Koketsu R, Sugiyama H, Masuda T, Kaname H, Egami Y, Nakayama T, Hasuo K, Nakamura H, Igari T, Watanabe K, Nagata N, Sakurai T, Yokoi C, Kobayakawa M, Kojima Y, Akiyama J, Imamura M, Masaki N, Yanase M
机构信息
Department of Gastroenterology, National Center for Global Health and Medicine, Tokyo, Japan.
Department of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
出版信息
Case Rep Gastroenterol. 2015 Apr 1;9(1):81-7. doi: 10.1159/000381140. eCollection 2015 Jan-Apr.
Small-cell lung cancer (SCLC) is a subgroup of lung cancer with a high frequency of liver metastasis, which is a predictor of poor prognosis. Diffuse liver metastases of SCLC with no visible nodular lesions in the liver when examined using computed tomography (CT) are relatively rare; however, a few cases with rapid progression to acute liver failure that were diagnosed after death have been reported. In this paper, we report a 63-year-old man with diffuse liver metastases of SCLC that were histologically diagnosed using a transjugular liver biopsy while the patient was alive, even though no lesions were visible during a contrast-enhanced CT examination.
小细胞肺癌（SCLC）是肺癌的一个亚组，肝转移发生率高，是预后不良的一个预测指标。小细胞肺癌发生弥漫性肝转移，在使用计算机断层扫描（CT）检查时肝脏未见明显结节性病变的情况相对少见；然而，已有少数病例报告在死后诊断为迅速进展至急性肝衰竭。在本文中，我们报告了一名63岁男性，患有小细胞肺癌弥漫性肝转移，在患者存活期间通过经颈静脉肝活检进行了组织学诊断，尽管在增强CT检查期间未见病变。
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