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含糖饮料与2型糖尿病之间的关联:一项荟萃分析。

Association between sugar-sweetened beverages and type 2 diabetes: A meta-analysis.

作者信息

Wang Meng, Yu Min, Fang Le, Hu Ru-Ying

机构信息

Zhejiang Provincial Center for Disease Control and Prevention Hangzhou City, China.

出版信息

J Diabetes Investig. 2015 May;6(3):360-6. doi: 10.1111/jdi.12309. Epub 2014 Dec 11.

Abstract

AIMS/INTRODUCTION: Many studies have been carried out to examine the association between sugar-sweetened beverages and the incident of type 2 diabetes, but results are mixed. The aim of the present study was to estimate the association between sugar-sweetened beverage intake and the risk of type 2 diabetes.

MATERIALS AND METHODS

PubMed, Springer Link and Elsevier databases were searched up to July 2014. Prospective studies published on the association between sugar-sweetened beverage intake and the risk of type 2 diabetes were included. The pooled relative risks (RRs) and 95% confidence intervals (CIs) for highest versus lowest category of sugar-sweetened beverages were estimated using a random-effects model.

RESULTS

The pooled effect estimate of sugar-sweetened beverage intake was 1.30 (95% confidence interval [CI] 1.21-1.39) for type 2 diabetes; stratified by geographic region of the studies, the pooled effect estimates were 1.34 (95% CI 0.74-2.43), 1.30 (95% CI 1.20-1.40), 1.29 (95% CI 1.09-1.53) in Asia, the USA and Europe,respectively; the pooled effect estimates were 1.26 (95% CI 1.16-1.36) with adjusting body mass index and 1.38 (95% CI 1.23-1.56) without adjusting body mass index.

CONCLUSIONS

Our findings suggested that sugar-sweetened beverage intake was associated with an increased risk of type 2 diabetes, and the association was attenuated by adjustment for body mass index. Specifically, the associations were also found to be significantly positive in the USA and Europe.

摘要

目的/引言:已开展多项研究来检验含糖饮料与2型糖尿病发病之间的关联,但结果不一。本研究的目的是评估含糖饮料摄入量与2型糖尿病风险之间的关联。

材料与方法

检索截至2014年7月的PubMed、Springer Link和Elsevier数据库。纳入已发表的关于含糖饮料摄入量与2型糖尿病风险之间关联的前瞻性研究。使用随机效应模型估计含糖饮料摄入量最高类别与最低类别相比的合并相对风险(RRs)及95%置信区间(CIs)。

结果

含糖饮料摄入量对2型糖尿病的合并效应估计值为1.30(95%置信区间[CI] 1.21 - 1.39);按研究的地理区域分层,在亚洲、美国和欧洲的合并效应估计值分别为1.34(95% CI 0.74 - 2.43)、1.30(95% CI 1.20 - 1.40)、1.29(95% CI 1.09 - 1.53);调整体重指数后的合并效应估计值为1.26(95% CI 1.16 - 1.36),未调整体重指数时为1.38(95% CI 1.23 - 1.56)。

结论

我们的研究结果表明,含糖饮料摄入量与2型糖尿病风险增加有关,且这种关联在调整体重指数后减弱。具体而言,在美国和欧洲也发现这种关联呈显著正相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e30b/4420570/d14e2253cce1/jdi0006-0360-f1.jpg

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