Kolter Thomas
Program Unit Membrane Biology & Lipid Biochemistry, LiMES, University of Bonn, Gerhard-Domagk Straße 1, 53121 Bonn, Germany.
ISRN Biochem. 2012 Dec 19;2012:506160. doi: 10.5402/2012/506160. eCollection 2012.
Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types. The paper provides a general overview on their structures, occurrence, and metabolism. Key functional, biochemical, and pathobiochemical aspects are summarized.
神经节苷脂是含唾液酸的糖鞘脂。它们尤其存在于神经元细胞的细胞表面,在那里形成复杂的模式,但也存在于许多其他细胞类型中。本文对其结构、存在情况和代谢进行了总体概述。总结了关键的功能、生化和病理生化方面的内容。