一对已婚夫妇同时发生的外阴癌和阴茎癌中16型人乳头瘤病毒的序列变异

Human papillomavirus type 16 sequence variation in concurrent vulvar and penile carcinoma in a married couple.

作者信息

Mitamura Takashi, Watari Hidemichi, Yamashiro Katsushige, Kato Tatsuya, Hosaka Masayoshi, Shimada Chisa, Fukumoto Shun, Noshiro Kiwamu, Sasaki Takayuki, Sakuragi Noriaki

机构信息

From the *Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo, Japan; †Division of Pathology, Hokkaido Cancer Center, Shiroishi-ku, Sapporo, Japan; and ‡Department of Gynecology, Hokkaido Cancer Society, Higashi-ku, Sapporo, Japan.

出版信息

Sex Transm Dis. 2015 Jun;42(6):342-3. doi: 10.1097/OLQ.0000000000000274.

DOI:10.1097/OLQ.0000000000000274

PMID:25970313

Abstract

We encountered an elderly married couple with concurrent vulvar and penile carcinoma with an Asian variant of human papillomavirus type 16. Asian variants might have an elevated risk of concurrent external genital carcinomas of a male and a female, and analysis of human papillomavirus variants might be important to understand the mechanism of carcinogenesis.

摘要

我们遇到一对老年夫妇，他们同时患有外阴癌和阴茎癌，且感染了16型人乳头瘤病毒的亚洲变体。亚洲变体可能会增加男性和女性同时发生外生殖器癌的风险，分析人乳头瘤病毒变体对于了解致癌机制可能很重要。