Cammaroto Giovanni, Quartuccio Natale, Sindoni Alessandro, Di Mauro Francesca, Caobelli Federico
Department of Otorhinolaryngology, University of Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Nuclear Medicine Unit, Department of Biomedical Sciences and Morphologic and Functional Images, University of Messina, Messina, Italy.
Eur Arch Otorhinolaryngol. 2016 Aug;273(8):1961-73. doi: 10.1007/s00405-015-3651-4. Epub 2015 May 14.
The management of head and neck tumor (HNSCC) has been changing over the years, especially due to the aid of imaging techniques that help physicians to attain a correct diagnosis. These techniques represent a valuable tool to help tailor treatment and during follow-up of patients affected by malignancies. The aim of this review is to summarize the results of the most recent and relevant studies about the use of PET imaging in HNSCCs. This review is divided into six chapters: (1) The role of PET/CT in the pre-treatment phase; (2) PET/CT and radiotherapy planning; (3) PET/CT in the post-treatment setting; (4) PET/CT and SUVmax for prediction of prognosis; (5) miscellanea on the utility of PET in specific HNSCCs; (6) non-FDG PET tracers used in HNSCC. Promising results have been obtained so far. Despite the encouraging outcomes, more investigations are needed to warrant the value of this technique, especially in the pre-treatment setting.
多年来，头颈部肿瘤（HNSCC）的管理方式一直在变化，特别是借助成像技术，这些技术有助于医生做出正确诊断。这些技术是帮助制定治疗方案以及对恶性肿瘤患者进行随访的宝贵工具。本综述的目的是总结关于PET成像在头颈部鳞状细胞癌中应用的最新及相关研究结果。本综述分为六章：（1）PET/CT在治疗前阶段的作用；（2）PET/CT与放射治疗计划；（3）治疗后环境中的PET/CT；（4）PET/CT和SUVmax用于预测预后；（5）PET在特定头颈部鳞状细胞癌中的应用杂项；（6）头颈部鳞状细胞癌中使用的非FDG PET示踪剂。到目前为止已经取得了有前景的结果。尽管结果令人鼓舞，但仍需要更多研究来证实这项技术的价值，特别是在治疗前环境中。
