Faron Matthew L, Ledeboer Nathan A, Granato Paul, Daly Judy A, Pierce Kristina, Pancholi Preeti, Uphoff Timothy S, Buchan Blake W
Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Laboratory Alliance of Central New York, Syracuse, New York, USA.
J Clin Microbiol. 2015 Jul;53(7):2365-7. doi: 10.1128/JCM.01085-15. Epub 2015 May 13.
We evaluated the clinical performance (sensitivity and specificity) of the AmpliVue group A Streptococcus (GAS) isothermal helicase-dependent amplification assay using 1,192 pharyngeal swab specimens. AmpliVue GAS assay results were compared to the results of routine throat cultures on selective streptococcal blood agar plates. The sensitivity and specificity of the AmpliVue GAS assay were 98.3% (95% confidence interval [CI], 95 to 100%) and 93.2% (95% CI, 91 to 95%), respectively.
我们使用1192份咽拭子标本评估了AmpliVue A组链球菌(GAS)等温解旋酶依赖性扩增检测法的临床性能(敏感性和特异性)。将AmpliVue GAS检测结果与选择性链球菌血琼脂平板上常规咽拭子培养结果进行比较。AmpliVue GAS检测法的敏感性和特异性分别为98.3%(95%置信区间[CI],95至100%)和93.2%(95%CI,91至95%)。