Baker Joseph F, Shafqat Asseer, Devitt Aiden, McCabe John P
Department of Trauma and Orthopaedic Surgery, Galway University Hospital, Galway, Ireland.
J Craniovertebr Junction Spine. 2015 Apr-Jun;6(2):56-9. doi: 10.4103/0974-8237.156041.
Metastatic spine disease is an ever-increasing burden on health care systems. Certain levels in the spine confer unique biomechanical characteristics and hence are of interest. Isolated C2 lesions are rare. We aimed to review our results in surgical management of C2 lesions.
We reviewed all surgical stabilizations of metastatic spine lesions over the preceding 4 years. Six patients with C2 lesions were identified. Of these five underwent surgical stabilization primarily for disease affecting the second cervical vertebra. Case notes and radiology were reviewed to determine presentation, outcomes and complications.
Cases were treated primarily by posterior instrumentation from either occiput or C1 to the subaxial cervical spine. The median survivorship after surgery was 283 days. There were no cases of infection, VTE or implant failure. There were no cases of neurologic deterioration with all maintaining Frankel E grading.
Metastatic lesions affecting the second cervical vertebra are rare. A variety of stabilization options tailored to the individual lesions, including occipitocervical fixation, in this small series was successful in maintaining stability and resolution of symptoms.
转移性脊柱疾病给医疗保健系统带来的负担日益加重。脊柱的某些节段具有独特的生物力学特性，因此备受关注。孤立的C2节段病变较为罕见。我们旨在回顾我们在C2节段病变手术治疗方面的结果。
我们回顾了过去4年中所有转移性脊柱病变的手术固定病例。确定了6例C2节段病变患者。其中5例主要因第二颈椎疾病接受手术固定。回顾病例记录和影像学资料以确定临床表现、治疗结果及并发症。
病例主要采用从枕骨或C1至颈椎下节段的后路内固定治疗。术后中位生存期为283天。无感染、静脉血栓栓塞症（VTE）或植入物失败病例。无神经功能恶化病例，所有患者均维持Frankel E级评分。
影响第二颈椎的转移性病变罕见。在这个小系列研究中，针对个体病变采用的多种固定方法，包括枕颈固定，成功维持了稳定性并缓解了症状。
