Buck Jordan M, Siegel Jessica A
Department of Psychology, Sewanee: The University of the South Sewanee, TN, USA.
Front Neurosci. 2015 Apr 29;9:151. doi: 10.3389/fnins.2015.00151. eCollection 2015.
Methamphetamine use among adolescents is a significant social and public health concern. Despite increased awareness of methamphetamine use among younger people, relatively little research has examined the effects of adolescent methamphetamine use compared to adult use. Thus, much remains to be learned about how methamphetamine alters adolescent brain function and behavior. In this article we review recent trends in adolescent methamphetamine use and data examining the effects of adolescent methamphetamine use on the dopaminergic system and behavior in humans and animal models. Future research is warranted to expand our understanding of the effects of adolescent methamphetamine exposure and how those effects differ from those seen in adults.
青少年使用甲基苯丙胺是一个重大的社会和公共卫生问题。尽管人们对年轻人使用甲基苯丙胺的认识有所提高,但与成年人使用情况相比,针对青少年使用甲基苯丙胺的影响进行的研究相对较少。因此,关于甲基苯丙胺如何改变青少年大脑功能和行为,仍有许多有待了解的地方。在本文中,我们回顾了青少年使用甲基苯丙胺的最新趋势,以及关于青少年使用甲基苯丙胺对人类和动物模型中多巴胺能系统及行为影响的数据。有必要进行未来研究,以扩大我们对青少年接触甲基苯丙胺的影响以及这些影响与成年人有何不同的理解。