Verrel Julius, Almagor Eilat, Schumann Frank, Lindenberger Ulman, Kühn Simone
Center for Lifespan Psychology, Max Planck Institute for Human Development Berlin, Germany.
The Jerusalem Academy of Music and Dance Jerusalem, Israel.
Front Hum Neurosci. 2015 Apr 28;9:232. doi: 10.3389/fnhum.2015.00232. eCollection 2015.
We use functional magnetic resonance imaging to investigate short-term neural effects of a brief sensorimotor intervention adapted from the Feldenkrais method, a movement-based learning method. Twenty-one participants (10 men, 19-30 years) took part in the study. Participants were in a supine position in the scanner with extended legs while an experienced Feldenkrais practitioner used a planar board to touch and apply minimal force to different parts of the sole and toes of their left foot under two experimental conditions. In the local condition, the practitioner explored movement within foot and ankle. In the global condition, the practitioner focused on the connection and support from the foot to the rest of the body. Before (baseline) and after each intervention (post-local, post-global), we measured brain activity during intermittent pushing/releasing with the left leg and during resting state. Independent localizer tasks were used to identify regions of interest (ROI). Brain activity during left-foot pushing did not significantly differ between conditions in sensorimotor areas. Resting state activity (regional homogeneity, ReHo) increased from baseline to post-local in medial right motor cortex, and from baseline to post-global in the left supplementary/cingulate motor area. Contrasting post-global to post-local showed higher ReHo in right lateral motor cortex. ROI analyses showed significant increases in ReHo in pushing-related areas from baseline to both post-local and post-global, and this increase tended to be more pronounced post-local. The results of this exploratory study show that a short, non-intrusive sensorimotor intervention can have short-term effects on spontaneous cortical activity in functionally related brain regions. Increased resting state activity in higher-order motor areas supports the hypothesis that the global intervention engages action-related neural processes.
我们使用功能磁共振成像来研究一种基于费登奎斯方法（一种基于运动的学习方法）改编的简短感觉运动干预的短期神经效应。21名参与者（10名男性，年龄在19至30岁之间）参与了该研究。参与者在扫描仪中仰卧，双腿伸直，在两种实验条件下，一名经验丰富的费登奎斯疗法从业者使用一块平板触摸并对其左脚脚底和脚趾的不同部位施加最小的力。在局部条件下，从业者探索足部和脚踝内部的运动。在整体条件下，从业者专注于足部与身体其他部位的连接和支撑。在每次干预前（基线）和干预后（局部干预后、整体干预后），我们测量了左腿间歇性推/放过程中和静息状态下的大脑活动。使用独立的定位任务来识别感兴趣区域（ROI）。在感觉运动区域，不同条件下左脚推压过程中的大脑活动没有显著差异。静息状态活动（局部一致性，ReHo）从基线到局部干预后在右侧内侧运动皮层增加，从基线到整体干预后在左侧辅助/扣带回运动区增加。将整体干预后与局部干预后进行对比，结果显示右侧外侧运动皮层的ReHo更高。ROI分析表明，从基线到局部干预后和整体干预后，与推压相关区域的ReHo均显著增加，并且这种增加在局部干预后往往更为明显。这项探索性研究的结果表明，一种简短、非侵入性的感觉运动干预可以对功能相关脑区的自发皮层活动产生短期影响。高阶运动区域静息状态活动的增加支持了这样一种假设，即整体干预涉及与动作相关的神经过程。
