Gordini Luca, Podda Francesco, Medas Fabio, Lai Maria Letizia, Longheu Alessandro, Pisano Giuseppe, Calò Pietro Giorgio
Department of Surgical Sciences, University of Cagliari, SS554 Bivio Sestu, 09042 Monserrato, Cagliari, Italy.
Ann Med Surg (Lond). 2015 Apr 23;4(2):129-32. doi: 10.1016/j.amsu.2015.04.019. eCollection 2015 Jun.
Thyroglossal duct cyst carcinomas are extremely rare and their clinical presentation is similar to that of benign cysts. The diagnosis is based on physical examination, laboratory tests, and most importantly multiple imaging techniques (ultrasonography, computed tomography and magnetic resonance imaging), and fine needle aspiration cytology.
We report a very unusual case of a tall cell variant of papillary carcinoma arising in a thyroglossal duct cyst in association with a follicular variant of papillary microcarcinoma and a tall cell variant of papillary carcinoma arising from the thyroid gland.
Although rarely described in the medical literature, ectopic thyroid tissue present in the thyroglossal duct cyst could be involved in the development of a poorly differentiated carcinoma. The frequent observation of an associated primitive thyroid carcinoma makes surgical management of thyroid gland controversial.
For the optimal management of this rare pathological condition, a comprehensive preoperative evaluation and meticulous intra-operative appraisal are fundamental.
甲状舌管囊肿癌极为罕见，其临床表现与良性囊肿相似。诊断基于体格检查、实验室检查，最重要的是多种影像学技术（超声、计算机断层扫描和磁共振成像）以及细针穿刺细胞学检查。
我们报告了一例非常罕见的病例，甲状舌管囊肿中出现乳头癌的高细胞变体，同时伴有甲状腺微小乳头癌的滤泡变体以及甲状腺原发的乳头癌高细胞变体。
尽管医学文献中对此描述较少，但甲状舌管囊肿中存在的异位甲状腺组织可能参与低分化癌的发生。经常观察到伴有原发性甲状腺癌使得甲状腺的手术管理存在争议。
对于这种罕见病理状况的最佳管理，全面的术前评估和细致的术中评估至关重要。
