Gebbia Vittorio, Di Gregorio Carlo, Attard Marco
Department of Experimental Oncology and Clinical Applications, University of Palermo, Italy.
J Med Case Rep. 2008 Apr 29;2:132. doi: 10.1186/1752-1947-2-132.
Thyroglossal duct carcinoma is a very rare finding and its presentation is similar to that of a benign cyst, which is a relatively common developmental abnormality that may manifest as a midline, neck mass. In general the diagnosis of thyroglossal duct carcinoma is based on the pathologic examination of the mass, but needle aspiration cytology, ultrasound and computed tomography play a role in the differential diagnosis of malignancy.
A further case of thyroglossal duct carcinoma and concurrent thyroid carcinoma with locoregional lymph node metastases affecting a 40-year-old woman followed up for 4 years is presented and discussed.
Sistrunk's surgical technique must always be the initial treatment, but in case of carcinoma further surgery, that is, thyroidectomy with or without lymph node dissection, and treatment with radioactive iodine have to be considered according to the microscopic and clinical findings. Accurate pre-operative clinical and radiological evaluation should be performed in order to plan surgical strategy.
甲状舌管癌是一种非常罕见的疾病，其表现与良性囊肿相似，良性囊肿是一种相对常见的发育异常，可表现为颈部中线肿块。一般来说，甲状舌管癌的诊断基于肿块的病理检查，但针吸细胞学检查、超声和计算机断层扫描在恶性肿瘤的鉴别诊断中发挥作用。
本文介绍并讨论了一例40岁女性甲状舌管癌合并甲状腺癌伴局部区域淋巴结转移的病例，该病例随访了4年。
Sistrunk手术技术必须始终作为初始治疗方法，但对于癌症患者，必须根据显微镜检查和临床发现考虑进一步的手术，即甲状腺切除术加或不加淋巴结清扫术，以及放射性碘治疗。应进行准确的术前临床和放射学评估，以制定手术策略。
