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一名63岁男性特发性双侧肾上腺出血:病例报告及文献复习

Idiopathic bilateral adrenal hemorrhage in a 63-year-old male: a case report and review of the literature.

作者信息

Dhawan Naveen, Bodukam Vijay Kumar, Thakur Kshitij, Singh Amandeep, Jenkins Donald, Bahl Jaya

机构信息

Nova Southeastern University Health Sciences Division, Fort Lauderdale, FL 33314-7796, USA.

Crozer-Chester Medical Center, Upland, PA 19013, USA.

出版信息

Case Rep Urol. 2015;2015:503638. doi: 10.1155/2015/503638. Epub 2015 Apr 21.

Abstract

Adrenal hemorrhage is a largely uncommon condition typically caused by a number of factors including infection, MI, CHF, anticoagulants, trauma, surgery, and antiphospholipid syndrome. Yet, idiopathic bilateral hemorrhage is rare. The authors present a case of a 63-year-old male who presented with abdominal pain that was eventually diagnosed as bilateral adrenal hemorrhages due to an unknown origin. Abdominal CT revealed normal adrenal glands without enlargement, but an MRI displayed enlargement due to hemorrhage in both adrenals. There was no known cause; the patient had not suffered from an acute infection and was not on anticoagulants, and the patient's history did not reveal any of the other known causative factors. The case underscores the importance of keeping bilateral adrenal hemorrhages on the list of differentials even when a cause is not immediately clear. It also raises the question of whether CT is the most sensitive test in the diagnosis of adrenal hemorrhage and whether the diagnostic approach should place greater weight on MRI. The case highlights the need for prompt therapy with steroids once bilateral hemorrhage is suspected to avert the development or progression of adrenal insufficiency.

摘要

肾上腺出血是一种相对罕见的病症,通常由多种因素引起,包括感染、心肌梗死、充血性心力衰竭、抗凝剂使用、外伤、手术以及抗磷脂综合征。然而,特发性双侧出血则较为罕见。作者报告了一例63岁男性病例,该患者因腹痛就诊,最终被诊断为双侧肾上腺出血,病因不明。腹部CT显示肾上腺正常,无增大,但MRI显示双侧肾上腺因出血而增大。病因不明;患者未患急性感染,未使用抗凝剂,其病史也未显示任何其他已知的致病因素。该病例强调了即使病因尚不明确,也需将双侧肾上腺出血列入鉴别诊断清单的重要性。它还引发了一个问题,即CT是否是诊断肾上腺出血最敏感的检查,以及诊断方法是否应更重视MRI。该病例突出了一旦怀疑双侧出血,需及时使用类固醇进行治疗以避免肾上腺功能不全的发生或进展的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e42a/4417992/3bafdf48b7e1/CRIU2015-503638.001.jpg

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