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一名中年女性特发性双侧肾上腺出血自发消退病例:1年随访

A CASE OF SPONTANEOUS REGRESSION OF IDIOPATHIC BILATERAL ADRENAL HEMORRHAGE IN A MIDDLE AGED WOMAN: 1 YEAR FOLLOW-UP.

作者信息

Song Y W, Yu H M, Park K S, Lee J M

机构信息

Research Institute of Clinical Medicine, Eulji University Hospital, Department of Internal Medicine, Daejeon, Republic of Korea.

出版信息

Acta Endocrinol (Buchar). 2016 Jan-Mar;12(1):85-90. doi: 10.4183/aeb.2016.85.

Abstract

BACKGROUND

Bilateral adrenal hemorrhage is a serious condition that can result in adrenal insufficiency, shock, acute adrenal crisis, and mortality if it is not managed with adequate treatment. We report a rare case of idiopathic bilateral adrenal hemorrhage.

CASE PRESENTATION

A 50-year-old woman visited our hospital with complaints of right upper abdominal pain. A computed tomography (CT) revealed unilateral left adrenal gland hemorrhage. However, the results of rapid adrenocorticotropic hormone (ACTH) stimulation test and adrenomedullary hormone function test were normal. Since the patient did not show signs of adrenal insufficiency, corticosteroid therapy was postponed and only supportive management therapy was started. After 1 week, a follow- up CT showed a previously unseen adrenal hemorrhage on the right adrenal gland, but the rapid ACTH stimulation test result was normal. One year later, no hemorrhagic signs were observed on the follow-up CT.

CONCLUSION

In most cases of idiopathic bilateral adrenal hemorrhage, patients are treated with steroid replacement therapy due to adrenal insufficiency. In some other cases, patients are treated with steroids despite the absence of adrenal insufficiency. Here we reported a very rare case of idiopathic bilateral adrenal hemorrhage sequentially to emphasize that before initiation of adrenal hormone replacement therapy, it is important to determine whether adrenal insufficiency is present. If there is no evidence of adrenal insufficiency, adrenal replacement therapy should be postponed until the presence of adrenal insufficiency is confirmed.

摘要

背景

双侧肾上腺出血是一种严重疾病,如果治疗不当,可导致肾上腺功能不全、休克、急性肾上腺危象甚至死亡。我们报告一例罕见的特发性双侧肾上腺出血病例。

病例介绍

一名50岁女性因右上腹疼痛前来我院就诊。计算机断层扫描(CT)显示左侧肾上腺单侧出血。然而,快速促肾上腺皮质激素(ACTH)刺激试验和肾上腺髓质激素功能试验结果正常。由于患者未表现出肾上腺功能不全的迹象,因此推迟了皮质类固醇治疗,仅开始了支持性治疗。1周后,随访CT显示右侧肾上腺出现了之前未发现的肾上腺出血,但快速ACTH刺激试验结果正常。1年后,随访CT未观察到出血迹象。

结论

在大多数特发性双侧肾上腺出血病例中,患者因肾上腺功能不全接受类固醇替代治疗。在其他一些病例中,即使没有肾上腺功能不全,患者也接受类固醇治疗。在此,我们报告了一例非常罕见的特发性双侧肾上腺出血病例,以此强调在开始肾上腺激素替代治疗之前,确定是否存在肾上腺功能不全非常重要。如果没有肾上腺功能不全的证据,应推迟肾上腺替代治疗,直到确认存在肾上腺功能不全。

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