Xian Ying, Peterson Eric D
Neurol Res. 2015 Sep;37(9):840-3. doi: 10.1179/1743132815Y.0000000046. Epub 2015 May 14.
Stroke remains one of the major killers worldwide. Addressing this epidemic will require combined efforts of researchers (bench, translational, clinical, epidemiologists, outcomes, and implementation scientists) as well as all forms of health care workers and policy experts. However, the translation of bench findings into bedside has been a challenge. Improved strategies for clinical research are needed to shorten the time required to translate bench findings into patient care. Large national or even globe stroke registries are uniquely positioned to advance the science by providing a rich data source for disease and post marketing surveillance, comparative effectiveness and safety research, and ultimately dissemination of clinical trials findings to routine clinical practice. Fostering innovative clinical research and implementation through international collaborations provides an unprecedented opportunity to tackle the globe of stroke.
中风仍然是全球主要的杀手之一。应对这一流行病需要研究人员(基础、转化、临床、流行病学家、结果和实施科学家)以及所有形式的医护人员和政策专家共同努力。然而,将基础研究成果转化为临床应用一直是一项挑战。需要改进临床研究策略,以缩短将基础研究成果转化为患者护理所需的时间。大型国家甚至全球中风登记处具有独特的地位,可以通过提供丰富的疾病和上市后监测、比较有效性和安全性研究数据源,最终将临床试验结果传播到常规临床实践,从而推动科学发展。通过国际合作促进创新临床研究和实施,为应对全球中风问题提供了前所未有的机会。