Silverstone Peter H, Bercov Marni, Suen Victoria Y M, Allen Andrea, Cribben Ivor, Goodrick Jodi, Henry Stu, Pryce Catherine, Langstraat Pieter, Rittenbach Katherine, Chakraborty Samprita, Engels Rutger C, McCabe Christopher
Department of Psychiatry, University of Alberta, Edmonton, Canada; Strategic Clinical Network for Addiction and Mental Health, Alberta Health Services, Edmonton, Alberta, Canada; Department of Finance and Statistical Analysis, University of Alberta, Edmonton, Canada.
Strategic Clinical Network for Addiction and Mental Health, Alberta Health Services, Edmonton, Alberta, Canada.
PLoS One. 2015 May 14;10(5):e0125527. doi: 10.1371/journal.pone.0125527. eCollection 2015.
We describe initial pilot findings from a novel school-based approach to reduce youth depression and suicidality, the Empowering a Multimodal Pathway Towards Healthy Youth (EMPATHY) program. Here we present the findings from the pilot cohort of 3,244 youth aged 11-18 (Grades 6-12). They were screened for depression, suicidality, anxiety, use of drugs, alcohol, or tobacco (DAT), quality-of-life, and self-esteem. Additionally, all students in Grades 7 and 8 (mean ages 12.3 and 13.3 respectively) also received an 8-session cognitive-behavioural therapy (CBT) based program designed to increase resiliency to depression. Following screening there were rapid interventions for the 125 students (3.9%) who were identified as being actively suicidal, as well as for another 378 students (11.7%) who were felt to be at higher-risk of self-harm based on a combination of scores from all the scales. The intervention consisted of an interview with the student and their family followed by offering a guided internet-based CBT program. Results from the 2,790 students who completed scales at both baseline and 12-week follow-up showed significant decreases in depression and suicidality. Importantly, there was a marked decrease in the number of students who were actively suicidal (from n=125 at baseline to n=30 at 12-weeks). Of the 503 students offered the CBT program 163 (32%) took part, and this group had significantly lower depression scores compared to those who didn't take part. There were no improvements in self-esteem, quality-of-life, or the number of students using DAT. Only 60 students (2% of total screened) required external referral during the 24-weeks following study initiation. These results suggest that a multimodal school-based program may provide an effective and pragmatic approach to help reduce youth depression and suicidality. Further research is required to determine longer-term efficacy, reproducibility, and key program elements.
ClinicalTrials.gov NCT02169960.
我们描述了一种新型的基于学校的减少青少年抑郁和自杀倾向方法——“增强青少年健康多模式途径”(EMPATHY)项目的初步试点研究结果。在此,我们展示了3244名11至18岁青少年(6至12年级)试点队列的研究结果。对他们进行了抑郁、自杀倾向、焦虑、药物、酒精或烟草使用(DAT)、生活质量和自尊方面的筛查。此外,所有7年级和8年级的学生(平均年龄分别为12.3岁和13.3岁)还接受了一个基于8节认知行为疗法(CBT)的项目,旨在提高对抑郁的恢复力。筛查后,对125名被确定为有积极自杀行为的学生(3.9%)以及另外378名根据所有量表得分综合判断有较高自残风险的学生(11.7%)进行了快速干预。干预包括与学生及其家人进行访谈,然后提供一个基于网络的引导式CBT项目。2790名在基线和12周随访时都完成量表的学生的结果显示,抑郁和自杀倾向显著降低。重要的是,有积极自杀行为的学生数量显著减少(从基线时的125人降至12周时的30人)。在提供CBT项目的503名学生中,163名(32%)参与了,与未参与的学生相比,这组学生的抑郁得分显著更低。自尊、生活质量或使用DAT的学生数量没有改善。在研究开始后的24周内,只有60名学生(占总筛查人数的2%)需要外部转诊。这些结果表明,基于学校的多模式项目可能为帮助减少青少年抑郁和自杀倾向提供一种有效且务实的方法。需要进一步研究以确定长期疗效、可重复性和关键项目要素。
ClinicalTrials.gov NCT02169960。