Kariya Taro, Ito Nobuko, Kitamura Takayuki, Yamada Yoshitsugu
From the Departments of *Cardiovascular Medicine and †Anesthesia and Pain Relief Center, The University of Tokyo Hospital, Tokyo, Japan; and ‡Department of Anesthesiology, Toho University Sakura Medical Center, Sakura, Chiba, Japan.
A A Case Rep. 2015 May 15;4(10):132-6. doi: 10.1213/XAA.0000000000000132.
Decompensated hepatic failure occurred in a patient with a rare blood type. The patient had extreme hemodilution due to massive bleeding during liver transplantation. A shortage of matched and universal donor blood prompted us to transfuse albumin and fresh frozen plasma for intravascular volume resuscitation. The lowest hemoglobin was 0.6 g/dL, accompanied by ST depression and a serum lactate of 100 mg/dL. The accuracy of the measured value of 0.6 g/dL was confirmed. However, the patient recovered from this critical situation after transfusion, and he was eventually discharged from the hospital without significant sequelae. Maintaining normovolemia, administering pure oxygen, ensuring appropriate anesthetic depth, and maintaining minimal inotropic support were essential for this patient's survival during massive bleeding.
一名血型罕见的患者发生了失代偿性肝衰竭。该患者在肝移植期间因大量出血出现了极度血液稀释。匹配的通用供体血液短缺促使我们输注白蛋白和新鲜冰冻血浆进行血管内容量复苏。最低血红蛋白为0.6 g/dL,伴有ST段压低和血清乳酸水平为100 mg/dL。0.6 g/dL的测量值准确性得到了确认。然而,患者输血后从这一危急情况中康复,最终出院且无明显后遗症。维持正常血容量、给予纯氧、确保适当的麻醉深度以及维持最小的正性肌力支持对该患者在大量出血期间的存活至关重要。