老年人中的儿童期疾病与多种疾病并存情况
Childhood Conditions and Multimorbidity Among Older Adults.
作者信息
Pavela Gregory, Latham Kenzie
机构信息
Office of Energetics, Nutrition Obesity Research Centre, University of Alabama at Birmingham.
Department of Sociology, Indiana University-Purdue University of Indianapolis.
出版信息
J Gerontol B Psychol Sci Soc Sci. 2016 Sep;71(5):889-901. doi: 10.1093/geronb/gbv028. Epub 2015 May 14.
OBJECTIVES
This research tests whether childhood conditions are associated with trajectories of chronic conditions among older adults.
METHODS
Using data from the Health and Retirement Study (1992-2008), a series of hierarchical linear models are used to estimate number of chronic conditions at survey midpoint and the rate of increase in chronic conditions across 18 years of data.
RESULTS
Results suggest that lower childhood socioeconomic status (SES) and poor childhood health are associated with increased number of chronic conditions; however, childhood SES is no longer associated with chronic conditions after adjustment for adult SES and adult health. Poor childhood health continues to be associated with total number of chronic conditions after adjustment for adult SES and health. Rate of change in chronic conditions was not associated with childhood conditions. Results from a multinomial logistic regression model further indicated that the association between childhood conditions and adult multimorbidity increased at higher levels of multimorbidity.
DISCUSSION
This research adds to the evidence that early life conditions have a lasting influence on adult health, and that their influence may be independent of adult health and SES.
目标
本研究旨在检验儿童时期的状况是否与老年人慢性病的发展轨迹相关。
方法
利用健康与退休研究（1992 - 2008年）的数据，采用一系列分层线性模型来估计调查中点时的慢性病数量以及18年数据中慢性病的增长速率。
结果
结果表明，儿童时期较低的社会经济地位（SES）和较差的健康状况与慢性病数量增加相关；然而，在对成人SES和成人健康进行调整后，儿童时期的SES与慢性病不再相关。在对成人SES和健康进行调整后，儿童时期较差的健康状况仍与慢性病总数相关。慢性病的变化率与儿童时期的状况无关。多项逻辑回归模型的结果进一步表明，在多病症程度较高的情况下，儿童时期的状况与成人多种疾病并存之间的关联增强。
讨论
本研究进一步证明，早期生活状况对成人健康有持久影响，且这种影响可能独立于成人健康和SES。
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