Liu Fred X, Flatt Shirley W, Pakiz Bilgé, Sedjo Rebecca L, Wolin Kathleen Y, Blair Cindy K, Demark-Wahnefried Wendy, Rock Cheryl L
Department of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA, USA.
Department of Community and Behavioral Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Support Care Cancer. 2016 Jan;24(1):173-180. doi: 10.1007/s00520-015-2761-2. Epub 2015 May 15.
Physical activity is associated with reduced risk and progression of breast cancer, and exercise can improve physical function, quality of life, and fatigue in cancer survivors. Evidence on factors associated with cancer survivors' adherence to physical activity guidelines from the American Cancer Society and the U.S. Department of Health and Human Services is mixed. This study seeks to help fill this gap in knowledge by examining correlates with physical activity among breast cancer survivors.
Overweight or obese breast cancer survivors (N = 692) were examined at enrollment into a weight loss intervention study. Questionnaires and medical record review ascertained data on education, race, ethnicity, menopausal status, physical activity, and medical history. Measures of anthropometrics and fitness level were conducted. Regression analysis examined associations between physical activity and demographic, clinical, and lifestyle factors.
Overall, 23% of women met current guidelines. Multivariate analysis revealed that body mass index (p = 0.03), emergency room visits in the past year (p = 0.04), and number of comorbidities (p = 0.02) were associated with less physical activity. Geographic region also was associated with level of physical activity (p = 0.02), with women in Alabama reporting significantly less activity than those in other participating regions.
The majority of overweight/obese breast cancer survivors did not meet physical activity recommendations. Physical activity levels were associated with degree of adiposity, geographic location, and number of comorbidities. The majority of overweight breast cancer survivors should be encouraged to increase their level of physical activity. Individualizing exercise prescriptions according to medical comorbidities may improve adherence.
身体活动与降低乳腺癌风险及病情进展相关，运动可改善癌症幸存者的身体功能、生活质量和疲劳状况。关于癌症幸存者遵循美国癌症协会和美国卫生与公众服务部身体活动指南相关因素的证据并不一致。本研究旨在通过调查乳腺癌幸存者身体活动的相关因素，填补这一知识空白。
对692名超重或肥胖的乳腺癌幸存者进行了一项减肥干预研究。通过问卷调查和病历审查确定了教育程度、种族、民族、绝经状态、身体活动和病史等数据。进行了人体测量和体能水平测量。回归分析研究了身体活动与人口统计学、临床和生活方式因素之间的关联。
总体而言，23%的女性符合当前指南。多变量分析显示，体重指数（p = 0.03）、过去一年的急诊就诊次数（p = 0.04）和合并症数量（p = 0.02）与身体活动较少有关。地理区域也与身体活动水平相关（p = 0.02），阿拉巴马州的女性报告的活动量明显低于其他参与地区的女性。
大多数超重/肥胖的乳腺癌幸存者未达到身体活动建议水平。身体活动水平与肥胖程度、地理位置和合并症数量有关。应鼓励大多数超重乳腺癌幸存者增加身体活动水平。根据合并症情况个性化制定运动处方可能会提高依从性。
