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摩洛哥东南部利什曼原虫所致皮肤利什曼病的控制

Control of cutaneous leishmaniasis caused by Leishmania major in south-eastern Morocco.

作者信息

Bennis Issam, De Brouwere Vincent, Ameur Btissam, El Idrissi Laamrani Abderrahmane, Chichaoui Smaine, Hamid Sahibi, Boelaert Marleen

机构信息

National School of Public Health, Rabat, Morocco.

Institute of Tropical Medicine, Antwerp, Belgium.

出版信息

Trop Med Int Health. 2015 Oct;20(10):1297-305. doi: 10.1111/tmi.12543. Epub 2015 Jun 7.

Abstract

OBJECTIVE

The incidence of cutaneous leishmaniasis (CL) caused by Leishmania major has increased in Morocco over the last decade, prompting the Ministry of Health to take intersectoral response measures including vector and reservoir control. The aim of this article was to describe the CL outbreak response measures taken in the province of Errachidia, where the reservoir of L. major, a sand rat (Meriones shawi), was targeted using strychnine-poisoned wheat baits from 2010 to 2012.

METHOD

We analysed routine surveillance data and other information using the data of the CL control programme.

RESULTS

We present data on the evolution and the extension of CL in this province as well as the epidemiological profile of the disease. Between 2004 and 2013, 7099 cases of CL were recorded in Errachidia Province, gradually affecting all districts. Our results demonstrate that more women were affected than men and that all age groups were represented.

CONCLUSION

Errachidia Province was the epicentre of the recent CL outbreak in Morocco. A notable decline in incidence rates was observed after 2011. The outbreak control measures may have contributed to this decline, as well as climatic trends or progressing herd immunity.

摘要

目的

过去十年间,摩洛哥由硕大利什曼原虫引起的皮肤利什曼病(CL)发病率有所上升,促使卫生部采取包括病媒和宿主控制在内的跨部门应对措施。本文旨在描述在埃尔拉希迪亚省采取的CL疫情应对措施,2010年至2012年期间,该省针对硕大利什曼原虫的宿主——一种沙鼠(肖氏子午沙鼠),使用了含士的宁的小麦诱饵。

方法

我们利用CL控制项目的数据,分析了常规监测数据及其他信息。

结果

我们展示了该省CL的演变、蔓延情况以及该病的流行病学特征。2004年至2013年期间,埃尔拉希迪亚省共记录了7099例CL病例,逐渐波及所有地区。我们的结果表明,女性受影响的人数多于男性,且各年龄组均有病例。

结论

埃尔拉希迪亚省是摩洛哥近期CL疫情的中心。2011年后发病率显著下降。疫情控制措施可能促成了这种下降,气候趋势或群体免疫力的提高也可能起到了作用。

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