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Quantitative microfluidic fluorescence microscopy to study vaso-occlusion in sickle cell disease.

作者信息

Jimenez Maritza A, Tutuncuoglu Egemen, Barge Suchitra, Novelli Enrico M, Sundd Prithu

机构信息

Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.

Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.

出版信息

Haematologica. 2015 Oct;100(10):e390-3. doi: 10.3324/haematol.2015.126631. Epub 2015 May 14.

DOI:10.3324/haematol.2015.126631
PMID:25975836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4591772/
Abstract
摘要

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本文引用的文献

1
Neutrophils scan for activated platelets to initiate inflammation.中性粒细胞扫描激活的血小板以启动炎症反应。
Science. 2014 Dec 5;346(6214):1234-8. doi: 10.1126/science.1256478. Epub 2014 Dec 4.
2
In vitro microfluidic model for the study of vaso-occlusive processes.用于研究血管阻塞过程的体外微流控模型。
Exp Hematol. 2015 Mar;43(3):223-8. doi: 10.1016/j.exphem.2014.10.015. Epub 2014 Nov 11.
3
Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation.中性粒细胞 AKT2 在血管炎症中的异质细胞-细胞相互作用中起调节作用。
J Clin Invest. 2014 Apr;124(4):1483-96. doi: 10.1172/JCI72305. Epub 2014 Mar 18.
4
Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies.镰状细胞病中的血管闭塞：病理生理学和新型靶向治疗。
Blood. 2013 Dec 5;122(24):3892-8. doi: 10.1182/blood-2013-05-498311. Epub 2013 Sep 19.
5
Neutrophil recruitment and function in health and inflammation.中性粒细胞在健康与炎症中的募集与功能。
Nat Rev Immunol. 2013 Mar;13(3):159-75. doi: 10.1038/nri3399.
6
'Slings' enable neutrophil rolling at high shear."吊索"可使中性粒细胞在高切变下滚动。
Nature. 2012 Aug 16;488(7411):399-403. doi: 10.1038/nature11248.
7
A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease.一种有效的口服 P 选择素阻断剂可改善镰状细胞病患者的微循环血流和内皮细胞损伤标志物。
Am J Hematol. 2012 May;87(5):536-9. doi: 10.1002/ajh.23147. Epub 2012 Apr 10.
8
A biophysical indicator of vaso-occlusive risk in sickle cell disease.镰状细胞病血管阻塞风险的生物物理指标。
Sci Transl Med. 2012 Feb 29;4(123):123ra26. doi: 10.1126/scitranslmed.3002738.
9
In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology.使用微流控技术体外模拟血液疾病中发生的微血管闭塞和血栓形成。
J Clin Invest. 2012 Jan;122(1):408-18. doi: 10.1172/JCI58753. Epub 2011 Dec 12.
10
Sickle-cell disease.镰状细胞病。
Lancet. 2010 Dec 11;376(9757):2018-31. doi: 10.1016/S0140-6736(10)61029-X. Epub 2010 Dec 3.