Ragab Ahmed, Hamed Hossam O, Alsammani Mohamed A, Shalaby Hend, Nabeil Hanan, Barakat Rafik, Fetih Ahmed N
Department of Obstetrics and Gynecology, Faculty of Medicine, Qassim University, Burraidah, Qassim Region, Saudi Arabia; Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Department of Obstetrics and Gynecology, Faculty of Medicine, Qassim University, Burraidah, Qassim Region, Saudi Arabia; Department of Obstetrics and Gynecology, Women's Health Hospital, Faculty of Medicine, Assiut University, Assiut, Egypt.
Int J Gynaecol Obstet. 2015 Aug;130(2):174-8. doi: 10.1016/j.ijgo.2015.03.025. Epub 2015 May 6.
To compare the expulsion rate of Nova-T380, Multiload 375, and Copper-T380A intrauterine contraceptive devices (IUCDs) inserted during cesarean delivery.
A comparative randomized study was conducted between January 1, 2013, and June 30, 2014, in three maternity centers in Egypt and Saudi Arabia. All women scheduled for an elective cesarean and accepting intraoperative insertion of an IUCD were randomly allocated to receive the Nova-T380 (group 1), Multiload 375 (group 2), or Cu-T380A (group 3) using a computer-generated table. Researchers and participants were not masked to the type of IUCD. Follow-up was for 1 year. The primary outcome was IUCD expulsion (complete or partial [i.e. displacement]).
Each group contained 40 participants. At 1 year, expulsion had been reported for 5 (13%) women in group 1, 2 (5%) in group 2, and 6 (15%) in group 3 (P>0.05 for all). The frequency of displacement was significantly lower in group 2 (5 [13%] participants) than in group 1 (15 [38%]; P=0.001) and group 3 (14 [35%]; P=0.008).
Despite a comparable risk of expulsion following IUCD insertion during cesarean delivery, the Multiload 375 device showed the lowest risk of displacement.
比较剖宫产术中插入的Nova-T380、Multiload 375和铜T380A宫内节育器（IUCD）的排出率。
2013年1月1日至2014年6月30日，在埃及和沙特阿拉伯的三个产科中心进行了一项比较随机研究。所有计划进行择期剖宫产并接受术中插入IUCD的妇女，使用计算机生成的表格随机分配接受Nova-T380（第1组）、Multiload 375（第2组）或铜T380A（第3组）。研究人员和参与者未对IUCD的类型进行盲法处理。随访1年。主要结局是IUCD排出（完全或部分[即移位]）。
每组有40名参与者。1年时，第1组有5名（13%）妇女报告排出，第2组有2名（5%），第3组有6名（15%）（所有P>0.05）。第2组（5名[13%]参与者）的移位频率显著低于第1组（15名[38%]；P=0.001）和第3组（14名[35%]；P=0.008）。
尽管剖宫产术中插入IUCD后排出风险相当，但Multiload 375装置的移位风险最低。
