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血浆采集系统:自体输血的新概念。

The plasma collection system: a new concept in autotransfusion.

作者信息

Tawes R L, Sydorak G R, Duvall T B, Scribner R G, Rosenman J E, Beare J P, Brown W H, Harris E J

机构信息

Vascular Surgery Associates, San Mateo, California 94401.

出版信息

Ann Vasc Surg. 1989 Oct;3(4):304-6. doi: 10.1016/S0890-5096(06)60150-7.

Abstract

We have used the Haemonetics Cell-Saver autotransfusion technique in over 6,500 cases since 1979, salvaging more than 11,000 units of packed red blood cells. Major utilization has been in cardiac, vascular, and orthopedic cases. Coagulopathy associated with hypothermia, shock, multiple transfusions, and the autotransfusion technique, which removes clotting factors and platelets, often necessitated use of fresh-frozen plasma and platelet packs postoperatively to control bleeding and clotting problems. However, this defeats the prevention of disease transmission, transfusion reaction, and autoimmunization. Haemonetics has recently developed a plasma collection system which salvages up to 1,000 cc of platelet-rich plasma. Early experience suggests this technique will not only decrease the incidence of postoperative bleeding but further decrease the use of homologous (bank) blood and components. A step-by-step guide to the plasma collection system is discussed. The plasma collection system augments the present autotransfusion technique that conserves red blood cells, thus making complete autologous blood transfusion a reality.

摘要

自1979年以来,我们已在6500多例手术中使用了Haemonetics细胞回收自体输血技术,回收了超过11000单位的浓缩红细胞。主要应用于心脏、血管和骨科手术。与低温、休克、多次输血以及去除凝血因子和血小板的自体输血技术相关的凝血障碍,常常使得术后需要使用新鲜冰冻血浆和血小板包来控制出血和凝血问题。然而,这违背了预防疾病传播、输血反应和自身免疫的目的。Haemonetics公司最近研发了一种血浆采集系统,该系统可回收多达1000立方厘米的富含血小板血浆。早期经验表明,这项技术不仅会降低术后出血的发生率,还会进一步减少同源(库存)血液及成分的使用。本文讨论了血浆采集系统的分步操作指南。该血浆采集系统改进了现有的保存红细胞的自体输血技术,从而使完全自体输血成为现实。

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