Graham Eva, Gariépy Geneviève, Burns Rachel J, Schmitz Norbert
Douglas Mental Health University Institute, 6875 Boul. Lasalle, Montreal, QC H4H 1R3, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Purvis Hall, 1020 Pine Ave. West, Montreal, QC H3A 1A2, Canada.
McGill Institute for Health and Social Policy, 1130 Pine Avenue West, Montreal, QC H3A 1A3, Canada.
Prev Med. 2015 Aug;77:74-9. doi: 10.1016/j.ypmed.2015.05.004. Epub 2015 May 12.
To describe the demographic, lifestyle, and health characteristics of older adults with prediabetes compared to those with normal glucose levels or diabetes.
Participants were from the English Longitudinal Study of Aging 2004-2005 (n=4168). Statistical analyses examined differences between people with prediabetes and 1) people with normal glucose levels and 2) people with diabetes. Design-based F-statistics and t-tests tested differences for each characteristic individually and multinomial logistic regression examined adjusted associations. Survey weighting and cluster information was used to generalize to the older English population.
Compared to people with normal glucose levels, people with prediabetes were older (RR=1.05 95% CI 1.04-1.07), more likely to be employed (RR=1.27 95% CI 1.01-1.60), more likely to smoke (RR=2.21 95% CI 1.74-2.80), and had higher BMIs (RR=1.08 95% CI 1.06-1.10). Compared to people with diabetes, people with prediabetes were more likely to be women (RR=2.12 95% CI 1.57-2.86), more likely to be employed (RR=1.54 95% CI 1.02-2.33), had lower BMIs (RR=0.95 95% CI 0.93-0.98), were less likely to have a cardiovascular condition (RR=0.34 95% CI 0.24-0.47), and had higher self-rated health (χ(2)=26.08, p<0.001).
Older adults with prediabetes have a unique set of characteristics that may inform prevention or intervention schemes.
描述与血糖水平正常或患有糖尿病的老年人相比，糖尿病前期老年人的人口统计学、生活方式和健康特征。
参与者来自2004 - 2005年英国老龄化纵向研究（n = 4168）。统计分析考察了糖尿病前期人群与1）血糖水平正常人群以及2）糖尿病患者之间的差异。基于设计的F统计量和t检验分别检验每个特征的差异，多项逻辑回归分析调整后的关联。使用调查权重和聚类信息以推广至英国老年人群体。
与血糖水平正常的人群相比，糖尿病前期人群年龄更大（风险比=1.05，95%置信区间1.04 - 1.07），就业可能性更高（风险比=1.27，95%置信区间1.01 - 1.60），吸烟可能性更高（风险比=2.21，95%置信区间1.74 - 2.80），且体重指数更高（风险比=1.08，95%置信区间1.06 - 1.10）。与糖尿病患者相比，糖尿病前期人群女性比例更高（风险比=2.12，95%置信区间1.57 - 2.86），就业可能性更高（风险比=1.54，95%置信区间1.02 - 2.33），体重指数更低（风险比=0.95，95%置信区间0.93 - 0.98），患心血管疾病的可能性更低（风险比=0.34，95%置信区间0.24 - 0.47），且自我健康评分更高（χ(2)=26.08，p<0.001）。
患有糖尿病前期的老年人具有一系列独特特征，这些特征可能为预防或干预方案提供依据。
