不同程度肝病患者血流感染的流行病学特征。
Epidemiological characteristics of bloodstream infections in patients with different degrees of liver disease.
机构信息
SC Virologia e Microbiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Biometric Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
出版信息
Infection. 2015 Oct;43(5):561-7. doi: 10.1007/s15010-015-0794-6. Epub 2015 May 15.
Observational retrospective study to evaluate the etiology, the outcome and the risk factors of bloodstream infections (BSIs) in patients with liver disease. One hundred and forty-eight BSIs were diagnosed (infection rate: 0.60 per 100 days of hospital stay), 62 BSIs (41.9 %) were associated with Gram-positive bacteria (infection rate: 0.25 per 100 days of hospital stay) and 80 (54.4 %) with Gram-negative bacteria (infection rate: 0.32 per 100 days of hospital stay). Admission-associated mortality was higher in patients with BSI than in those without BSI (20.6 versus 5.0 %, p < 0.001). Patients with cirrhosis had an increased risk to develop a BSI compared with patients with chronic hepatitis, specifically for Gram-positive (and Staphylococcus spp)-related BSI.
一项观察性回顾性研究旨在评估肝病患者血流感染（BSI）的病因、结果和危险因素。共诊断出 148 例 BSI（感染率：每住院 100 天 0.60 例），62 例 BSI（41.9%）与革兰阳性菌有关（感染率：每住院 100 天 0.25 例），80 例（54.4%）与革兰阴性菌有关（感染率：每住院 100 天 0.32 例）。与无 BSI 的患者相比，BSI 患者的入院相关死亡率更高（20.6%比 5.0%，p<0.001）。与慢性肝炎患者相比，肝硬化患者发生 BSI 的风险增加，特别是与革兰阳性菌（和金黄色葡萄球菌相关的）BSI 相关。
Zotero 插件