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[不同频率和潮气量人工通气时肺血管的微循环]

[Microcirculation in the pulmonary vessels during artificial ventilation of different frequencies and volumes].

作者信息

Kulik A M, Tkachenko S B, Nikulin V G

出版信息

Biull Eksp Biol Med. 1989 Oct;108(10):392-5.

PMID:2597747
Abstract

In acute experiments on cats with closed chest by means of biomicroscopic method it has been shown that artificial ventilation of increased frequency or volume causes the decrease of diameters of arterioles, venules, wide capillaries and also the decrease of the length of functional narrow capillaries. The constriction degree of arterioles and venules depends on their initial diameter. The length of the functional narrow capillaries is being changed to the great extent under frequency increase. Decrease of the volume of the artificial ventilation causes differently directed changes of these parameters in various regions of the lungs. It is supposed that other neuro-humoral factors take part in the realization of the determined changes except alveolar pressure.

摘要

在通过生物显微镜法对猫进行的急性闭胸实验中,已表明增加频率或容量的人工通气会导致小动脉、小静脉、宽毛细血管直径减小,以及功能性狭窄毛细血管长度缩短。小动脉和小静脉的收缩程度取决于它们的初始直径。在频率增加时,功能性狭窄毛细血管的长度会发生很大变化。人工通气量的减少会使肺部不同区域的这些参数发生不同方向的变化。据推测,除肺泡压力外,其他神经体液因素也参与了所确定变化的实现。

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