Tkachenko S B, Kulik A M
Patol Fiziol Eksp Ter. 1990 Jan-Feb(1):30-2.
Acute experiments were conducted on male cats with a closed chest by the biomicroscopic method to study the effect of artificial ventilation (AV) of increased frequency and volume on the diameter and length of the pulmonary microvessels and the character of blood flow in them during the development of pulmonary edema induced by intravenous infusion of a fatty acid mixture. It is shown that AV of increased frequency inhibits the reduction of the length of the functioning narrow capillaries and dilatation of the wide capillaries of the lungs as compared to the initial ventilation parameters and prevents a change in the directions of the blood flow in the pulmonary arterioles after exposure to the edematogenic effect. The diameter of the arterioles and venules reduces and that of the wide capillaries increases at the beginning of edema more in AV of increased volume than in ventilation of the initial parameters. It is assumed that AV of increased frequency is more effective than ventilation of increased volume in preventing pulmonary microcirculatory disorders in edema of the lungs.
采用生物显微镜方法，对雄性闭胸猫进行急性实验，以研究在静脉输注脂肪酸混合物诱发肺水肿过程中，增加频率和潮气量的人工通气（AV）对肺微血管直径和长度以及其中血流特性的影响。结果表明，与初始通气参数相比，增加频率的人工通气可抑制功能性狭窄毛细血管长度的缩短和肺宽毛细血管的扩张，并防止在受到致水肿作用后肺小动脉中血流方向的改变。在水肿开始时，增加潮气量的人工通气比初始参数通气时，小动脉和小静脉的直径减小，宽毛细血管的直径增加更明显。据推测，在预防肺水肿时的肺微循环障碍方面，增加频率的人工通气比增加潮气量的通气更有效。
