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来自阿尔及利亚撒哈拉地区的二歧翼萼花的化学成分、抗氧化和抗菌特性

Chemical composition, antioxidant and antibacterial properties of Pteranthus dichotomus from Algerian Sahara.

作者信息

Allaoua Zina, Benkhaled Mohammed, Dibi Ammar, Long Christophe, Aberkane Mohammed Cherif, Bouzidi Soumia, Kassah-Laouar Ahmed, Haba Hamada

机构信息

a Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Département de Chimie, Faculté des Sciences , Université de Batna, Batna , Algérie.

b USR 3388 CNRS-Pierre Fabre , 3 Avenue Hubert Curien BP 13562, Toulouse 31035 , France.

出版信息

Nat Prod Res. 2016;30(6):700-4. doi: 10.1080/14786419.2015.1038811. Epub 2015 May 15.

DOI:10.1080/14786419.2015.1038811
PMID:25978697
Abstract

The phytochemical study of ethyl acetate and n-butanol extracts of Pteranthus dichotomus Forssk. led to the isolation and identification of 11 compounds, including three glycolipids 1-3, one lignan 4, three flavonoids 5-7 and four phytosterols 8-11. Structures of the isolated compounds have been elucidated by analysis of 1D and 2D NMR data, and mass spectrometry EI-MS and ESI-MS and by comparison with literature data. Furthermore, the ethyl acetate and n-butanol extracts were examined for their antioxidant and antibacterial activities. The results showed that both extracts (PDAC and PDBU) had a moderate antioxidant activity (IC50 = 375.514 μg/mL and 691.333 μg/mL) respectively.

摘要

对二歧翼萼(Pteranthus dichotomus Forssk.)乙酸乙酯提取物和正丁醇提取物的植物化学研究,导致分离并鉴定出11种化合物,包括三种糖脂1 - 3、一种木脂素4、三种黄酮类化合物5 - 7和四种植物甾醇8 - 11。通过一维和二维核磁共振数据、质谱电子轰击质谱(EI-MS)和电喷雾电离质谱(ESI-MS)分析,并与文献数据比较,阐明了分离出的化合物的结构。此外,还检测了乙酸乙酯提取物和正丁醇提取物的抗氧化和抗菌活性。结果表明,两种提取物(PDAC和PDBU)分别具有中等抗氧化活性(IC50 = 375.514 μg/mL和691.333 μg/mL)。

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