Clesse Florence, Leray Emmanuelle, Bodeau-Livinec Florence, Husky Mathilde, Kovess-Masfety Viviane
Epidemiology department, EHESP, EA4057 Paris Descartes University, Sorbonne Paris Cité, France.
Epidemiology department, EHESP, EA4057 Paris Descartes University, Sorbonne Paris Cité, France; INSERM U1153, Equipe de recherche en Epidémiologie Obstétricale, Périnatale et Pédiatrique (EPOPé), France; Centre de Recherche Epidémiologie et Statistique Sorbonne Paris Cité (CRESS), France.
J Affect Disord. 2015 Aug 15;182:82-90. doi: 10.1016/j.jad.2015.04.039. Epub 2015 Apr 30.
DSM-V has been criticized for excessively expanding criteria for bereavement-related depression. The aim of this study was to quantify a potential increase in depression prevalence due to changes in diagnostic criteria and to assess the severity, clinical profile and healthcare use of new cases.
A cross-sectional telephone survey was performed in 2005-2006 in four French regions. Twelve-month prevalence of psychiatric disorders was measured by CIDI-SF. Bereavement was assessed in those who endorsed the gate question to the depression module. Persons with bereavement-related depression according to DSM-IV and DSM-V diagnosis criteria were compared.
Of the 22,138 respondents, 692 were bereaved. The prevalence of depression among those bereaved was 49.9% (95% CI ¼=43.7−56.0) according to DSM-IV and 59.6% (53.1−66.1) according to DSM-V [corrected]. The overall prevalence of major depression increased from 8.6% (8.1–9.1) with DSM-IV to 8.8% (8.3−9.3) with DSM-V . Cases diagnosed using DSM-IV presented more symptoms than cases diagnosed using DSM-V but clinical features were similar except regarding criterion E׳s symptoms. Healthcare use was similar between the two groups regarding consultations and psychotropic drug prescription.
Some DSM-IV and DSM-V criteria were difficult to operationalize in the survey. The observed difference in prevalence according to DSM-IV and DSM-V may be reduced when clinical judgment is taken into account.
The overall prevalence of major depression is only marginally increased by the new criteria. However, diagnostic changes increase the prevalence by 10 points among those bereaved. Diagnostic changes do not appear to modify service use.
《精神疾病诊断与统计手册》第五版(DSM-V)因过度扩大与丧亲相关抑郁症的诊断标准而受到批评。本研究的目的是量化因诊断标准变化导致的抑郁症患病率潜在增加情况,并评估新病例的严重程度、临床特征及医疗服务利用情况。
2005 - 2006年在法国四个地区进行了一项横断面电话调查。使用复合性国际诊断交谈检查表简版(CIDI-SF)测量精神障碍的12个月患病率。在认可抑郁症模块入门问题的人群中评估丧亲情况。比较了根据《精神疾病诊断与统计手册》第四版(DSM-IV)和DSM-V诊断标准诊断为与丧亲相关抑郁症的患者。
在22138名受访者中,692人经历了丧亲之痛。根据DSM-IV,丧亲者中抑郁症的患病率为49.9%(95%置信区间=43.7−56.0),根据DSM-V[校正后]为59.6%(53.1−66.1)。重度抑郁症的总体患病率从DSM-IV时的8.6%(8.1–9.1)增至DSM-V时的8.8%(8.3−9.3)。使用DSM-IV诊断的病例比使用DSM-V诊断的病例表现出更多症状,但除了标准E的症状外,临床特征相似。两组在咨询和精神药物处方方面的医疗服务利用情况相似。
一些DSM-IV和DSM-V标准在调查中难以实施。考虑临床判断时,根据DSM-IV和DSM-V观察到的患病率差异可能会减小。
新的诊断标准仅使重度抑郁症的总体患病率略有增加。然而,诊断标准的变化使丧亲者中的患病率增加了10个百分点。诊断标准的变化似乎并未改变医疗服务的使用情况。