Allsopp M, Verduyn C
Park Hospital for Children, Headington, Oxford.
Br J Psychiatry. 1989 Jun;154:829-34. doi: 10.1192/bjp.154.6.829.
Twenty-six patients seen at a regional adolescent psychiatry unit between 1974 and 1979 with a discharge diagnosis of obsessive-compulsive disorder were followed up after an average of ten years. Of 24 subjects traced, outcome information was obtained from 20. At the point of follow-up, ten patients remained psychiatrically ill, six having persisting obsessive-compulsive symptoms. Poor outcome was associated with a family history of psychiatric illness and lack of response to therapy at initial contact. All patients who were asymptomatic at discharge had remained well.
1974年至1979年间,一家地区青少年精神病科收治了26例出院诊断为强迫症的患者,平均随访10年。在追踪到的24名研究对象中,从20名那里获得了随访结果信息。在随访时,10名患者仍患有精神疾病,其中6名有持续的强迫症状。预后不良与精神疾病家族史以及初次接触时对治疗无反应有关。所有出院时无症状的患者均保持良好状态。