头颈部皮肤恶性肿瘤

Cutaneous malignancy of the head and neck.

作者信息

Mydlarz Wojciech K, Weber Randal S, Kupferman Michael E

机构信息

Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

出版信息

Surg Oncol Clin N Am. 2015 Jul;24(3):593-613. doi: 10.1016/j.soc.2015.03.010. Epub 2015 Apr 8.

DOI:10.1016/j.soc.2015.03.010

PMID:25979402

Abstract

Most skin cancers of the head and neck are nonmelanoma skin cancers (NMSCs). Basal cell carcinoma and squamous cell carcinoma are the most frequent types of NMSCs. Treatment options including wide local excision, Mohs surgery, sentinel lymph node biopsy, and cervical lymphadenectomy and adjuvant radiation when warranted offer a high cure rate, while balancing excellent functional and cosmetic outcomes. Evaluation by a multidisciplinary team is highly recommended with advanced and aggressive lesions. Avoidance of sunburns and acute sun damage, sunscreen protection, and early identification and evaluation of suspicious lesions remain the first line of defense against skin cancers.

摘要

头颈部的大多数皮肤癌是非黑色素瘤皮肤癌（NMSC）。基底细胞癌和鳞状细胞癌是最常见的NMSC类型。治疗选择包括广泛局部切除、莫氏手术、前哨淋巴结活检、颈部淋巴结清扫术以及在必要时进行辅助放疗，这些方法在保证高治愈率的同时，还能兼顾良好的功能和美容效果。对于晚期和侵袭性病变，强烈建议由多学科团队进行评估。避免晒伤和急性阳光损伤、使用防晒霜保护、早期识别和评估可疑病变仍然是预防皮肤癌的第一道防线。