大唾液腺肿瘤

Cancers of major salivary glands.

作者信息

Panwar Aru, Kozel Jessica A, Lydiatt William M

机构信息

Division of Head and Neck Surgery, University of Nebraska Medical Center, 600 S, 42nd Street, Omaha, NE 68198, USA.

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.

出版信息

Surg Oncol Clin N Am. 2015 Jul;24(3):615-33. doi: 10.1016/j.soc.2015.03.011.

DOI:10.1016/j.soc.2015.03.011

PMID:25979403

Abstract

Major salivary gland malignancies are a rare but histologically diverse group of entities. Establishing the diagnosis of a malignant salivary neoplasm may be challenging because of the often minimally symptomatic nature of the disease, and limitations of imaging modalities and cytology. Treatment is centered on surgical therapy and adjuvant radiation in selected scenarios. Systemic therapy with chemotherapeutic agents and monoclonal antibodies lacks evidence in support of its routine use.

摘要

大唾液腺恶性肿瘤是一组罕见但组织学上多样的实体。由于该疾病通常症状轻微，以及成像方式和细胞学的局限性，确立唾液腺恶性肿瘤的诊断可能具有挑战性。治疗以手术治疗为中心，并在特定情况下辅以放疗。使用化疗药物和单克隆抗体的全身治疗缺乏支持其常规使用的证据。