Antonello Vicente Sperb, Antonello Ivan Carlos Ferreira, Grossmann Thiago Kreutz, Tovo Cristiane Valle, Pupo Bruna Brasil Dal, Winckler Lisiane de Quadros
IAPI HIV Clinic, Porto Alegre, Brazil; Department of Infection Prevention and Control, Hospital Fêmina, Porto Alegre, Brazil; Post Graduate Course in Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Graduate Program in Medicine and Health Sciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
J Am Soc Hypertens. 2015 May;9(5):403-7. doi: 10.1016/j.jash.2015.03.008. Epub 2015 Mar 28.
Patients with HIV may have an increased risk of hypertension and cardiovascular disease (CVD). The objective of this study was to determine the prevalence and risk factors for hypertension in a population of HIV-infected patients at an HIV/AIDS clinic in southern Brazil. We reviewed medical records of 1009 HIV-infected patients aged 18 years or more in an urban HIV/AIDS clinic based in Porto Alegre, southern Brazil. Hypertension was defined according to the Eighth Joint National Committee criteria. The prevalence of hypertension in this study cohort was 22.5% (95% confidence interval, 20%-25.2%). Individuals were significantly older in the hypertensive group (P < .001). After adjustment using a Poisson regression model of all variables that presented P < .2 in the univariate analysis, the variables that were significantly associated with hypertension were only age ≥40 years and obesity. Also in this setting, dyslipidemia (P = .068) showed a tendency of association with hypertension. Compared with HIV-infected persons aged 18-39 years, those aged 40-59 years presented a 2-fold higher prevalence of hypertension (95% confidence interval, 1.2-3.3).The present study showed a high prevalence of hypertension among HIV-infected persons, similar to other studies, ranging from 13% to 45%, and also similar to the HIV-negative general population. Age and obesity were the factors associated with hypertension. Finally, the present study indicates a similar pattern of behavior and comorbidities for HIV-positive and -negative patients in relation to hypertension.
感染艾滋病毒的患者患高血压和心血管疾病（CVD）的风险可能会增加。本研究的目的是确定巴西南部一家艾滋病毒/艾滋病诊所中感染艾滋病毒患者群体中高血压的患病率和危险因素。我们回顾了巴西南部阿雷格里港一家城市艾滋病毒/艾滋病诊所中1009名18岁及以上感染艾滋病毒患者的病历。高血压根据美国国家联合委员会第八版标准定义。本研究队列中高血压的患病率为22.5%（95%置信区间，20%-25.2%）。高血压组患者的年龄显著更大（P < .001）。在对单变量分析中P < .2的所有变量使用泊松回归模型进行调整后，与高血压显著相关的变量仅为年龄≥40岁和肥胖。同样在此环境下，血脂异常（P = .068）显示出与高血压相关的趋势。与18-39岁的艾滋病毒感染者相比，40-59岁的感染者高血压患病率高出2倍（95%置信区间，1.2-3.3）。本研究显示艾滋病毒感染者中高血压的患病率很高，与其他研究相似，范围在13%至45%之间，也与艾滋病毒阴性的普通人群相似。年龄和肥胖是与高血压相关的因素。最后，本研究表明艾滋病毒阳性和阴性患者在高血压方面的行为模式和合并症相似。
