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2005-2017 年南非艾滋病毒感染者中高血压和糖尿病的趋势、流行率及相关因素。

Trends, prevalence and factors associated with hypertension and diabetes among South African adults living with HIV, 2005-2017.

机构信息

Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Human Sciences Research Council, Pretoria, South Africa.

出版信息

BMC Public Health. 2021 Mar 6;21(1):462. doi: 10.1186/s12889-021-10502-8.

Abstract

BACKGROUND

Many people are now living longer with HIV due to access to antiretroviral treatment. In turn, there has been an increase in the burden of hypertension and diabetes. The paucity of data on the burden of hypertension and diabetes in adults living with HIV in South Africa is a public health concern. The paper aimed to describe the prevalence and factors associated with hypertension and diabetes among adults living with HIV (ALHIV).

METHODS

This was a secondary data analysis of the population based on the South African National HIV Prevalence, Incidence, Behaviour and Communication surveys for 2005, 2008 and 2017. Descriptive statistics were used to summarise the characteristics of the study sample. Bivariate and multivariate logistic regression analyses were used to determine factors associated with hypertension and diabetes.

RESULTS

The total study population of ALHIV aged 25 years and older was 978, 1023 and 2483 for 2005, 2008 and 2017. The prevalence of hypertension showed an increasing trend at 11.8% in 2005, 9.5% in 2008 and 14.3% in 2017. The prevalence of diabetes was 3.3% in 2005, 2.8% in 2008 and 3.2% in 2017. Increased odds of hypertension among adults living with HIV were consistently associated with being female and the age group 45 years older across all the survey years, including pensioners and the sick, living in urban areas, high risk of hazardous alcohol consumption, diabetes and heart disease. Increased odds of diabetes were consistently associated with hypertension across all the survey years, including age group 45 years and older, and poor health. While having a secondary level of education and above was protective against diabetes.

CONCLUSION

The study showed that the prevalence of hypertension is high and has increased over time among adults living with HIV while the prevalence of diabetes has remained constant. Findings identified factors consistently associated with the prevalence of both diseases overtime, including contemporary risk factors that should be targeted in the integrated management of chronic disease and HIV care model.

摘要

背景

由于抗逆转录病毒治疗的普及,现在有越来越多的人能够在感染艾滋病毒的情况下长寿。随之而来的是高血压和糖尿病负担的增加。南非艾滋病毒感染者中高血压和糖尿病负担的数据稀缺,这是一个公共卫生关注点。本文旨在描述南非艾滋病毒感染者(ALHIV)中高血压和糖尿病的流行情况及相关因素。

方法

这是基于南非全国艾滋病毒流行率、发病率、行为和通讯调查 2005 年、2008 年和 2017 年的数据进行的二次数据分析。采用描述性统计方法对研究样本的特征进行总结。采用二变量和多变量逻辑回归分析确定与高血压和糖尿病相关的因素。

结果

2005 年、2008 年和 2017 年,年龄在 25 岁及以上的 ALHIV 总研究人群分别为 978、1023 和 2483 人。高血压的患病率呈上升趋势,分别为 2005 年的 11.8%、2008 年的 9.5%和 2017 年的 14.3%。糖尿病的患病率分别为 2005 年的 3.3%、2008 年的 2.8%和 2017 年的 3.2%。在所有调查年份中,高血压的成年人艾滋病毒感染者中,女性和 45 岁及以上年龄组的风险始终较高,包括养老金领取者和患病者,居住在城市地区,有高危危险的酒精消费、糖尿病和心脏病。在所有调查年份中,高血压与糖尿病的发生风险均呈正相关,包括 45 岁及以上年龄组和较差的健康状况。而接受过中等教育及以上教育则可以预防糖尿病。

结论

研究表明,高血压在艾滋病毒感染者中的患病率较高,且随着时间的推移而增加,而糖尿病的患病率则保持不变。研究结果确定了与两种疾病流行相关的因素,这些因素随着时间的推移始终保持一致,包括应在慢性病和艾滋病毒护理综合管理模型中针对的当代风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac7d/7937211/156a90af344b/12889_2021_10502_Fig1_HTML.jpg

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