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红细胞多不饱和脂肪酸水平在极有可能患精神病障碍的年轻人和健康青少年对照者中的研究。

Erythrocyte polyunsaturated fatty acid levels in young people at ultra-high risk for psychotic disorder and healthy adolescent controls.

机构信息

Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, The University of Melbourne, Australia.

Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

出版信息

Psychiatry Res. 2015 Jul 30;228(1):174-6. doi: 10.1016/j.psychres.2015.04.036. Epub 2015 May 2.

DOI:10.1016/j.psychres.2015.04.036
PMID:25979466
Abstract

Erythrocyte polyunsaturated fatty acid (PUFA) levels from individuals at ultra-high risk (UHR) for psychosis (n = 80) were compared to existing data from healthy controls (n = 142). Results demonstrated PUFA deficits (α-linolenic acid, eicosapentanoic acid, all ω-6 PUFAs) for the UHR group. Findings provide a rationale for PUFA based interventions in emerging psychosis.

摘要

将个体极有可能患精神病（UHR）的红细胞多不饱和脂肪酸（PUFA）水平与健康对照组（n = 142）的现有数据进行比较。结果表明 UHR 组存在 PUFA 缺乏（α-亚麻酸、二十碳五烯酸、所有 ω-6 PUFA）。这些发现为早期精神病的 PUFA 干预提供了依据。

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