Jha Sunita R, Ha Hakeem S K, Hickman Louise D, Hannu Malin, Davidson Patricia M, Macdonald Peter S, Newton Phillip J
Faculty Health, Centre for Cardiovascular and Chronic Care, University of Technology Sydney, Sydney, Australia,
Heart Fail Rev. 2015 Sep;20(5):553-60. doi: 10.1007/s10741-015-9493-8.
Frailty is a common geriatric syndrome of increased vulnerability to adverse events. The prevalence of frailty among chronic heart failure (CHF) is high and confers a greater risk of adverse events including falls, hospitalisation and mortality. There have been few studies assessing frailty in CHF. A review of the key databases was conducted from 2004 to 2014 including the key search terms 'frail elderly' and 'heart failure'. The following electronic databases were searched: Medline, Cumulative Index for Nursing and Allied Health and Academic Search Complete, with reference lists being manually searched. Articles were included if frailty was assessed using a valid measuring tool in a population with a confirmed diagnosis of CHF. The search yielded a total of 393 articles with 8 articles being selected for review. The prevalence of frailty among those with CHF was high, ranging from 18 to 54 %. The frailty phenotype and geriatric assessments tools were the most common frailty measures utilised; high rates of co-morbidity, hospitalisation and mortality were identified. Frailty is common in CHF and is associated with adverse outcomes.
衰弱是一种常见的老年综合征，对不良事件的易感性增加。慢性心力衰竭（CHF）患者中衰弱的患病率很高，且会增加包括跌倒、住院和死亡在内的不良事件风险。评估CHF患者衰弱情况的研究较少。2004年至2014年对主要数据库进行了检索，检索词包括“衰弱老年人”和“心力衰竭”。检索了以下电子数据库：医学索引数据库（Medline）、护理学与健康相关学科累积索引数据库（Cumulative Index for Nursing and Allied Health）和学术搜索完整版数据库（Academic Search Complete），并对参考文献列表进行了人工检索。如果在确诊为CHF的人群中使用有效的测量工具评估衰弱情况，则纳入相关文章。检索共得到393篇文章，其中8篇被选作综述。CHF患者中衰弱的患病率很高，在18%至54%之间。衰弱表型和老年评估工具是最常用的衰弱测量方法；共病、住院和死亡率较高。衰弱在CHF中很常见，且与不良结局相关。
