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The MTNR1B gene polymorphism rs10830963 is associated with gestational diabetes in a Brazilian population.

作者信息

Junior João Paulo Lobo, Frigeri Henrique R, Dos Santos-Weiss Izabella C R, de Souza Emanuel M, Rego Fabiane G M, Picheth Geraldo, Alberton Dayane

机构信息

Graduate Program in Pharmaceutical Sciences, Department of Clinical Analysis, Federal University of Parana (UFPR), Curitiba, PR, Brazil.

Department of Biochemistry and Molecular Biology, UFPR, Curitiba, PR, Brazil.

出版信息

Gene. 2015 Aug 15;568(1):114-5. doi: 10.1016/j.gene.2015.05.024. Epub 2015 May 14.

DOI:10.1016/j.gene.2015.05.024
PMID:25982863
Abstract
摘要

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1
The MTNR1B gene polymorphism rs10830963 is associated with gestational diabetes in a Brazilian population.MTNR1B基因多态性rs10830963与巴西人群的妊娠期糖尿病相关。
Gene. 2015 Aug 15;568(1):114-5. doi: 10.1016/j.gene.2015.05.024. Epub 2015 May 14.
2
MTNR1A and MTNR1B gene polymorphisms in women with gestational diabetes.妊娠期糖尿病女性的MTNR1A和MTNR1B基因多态性
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MTNR1B genetic polymorphisms as risk factors for gestational diabetes mellitus: a case-control study in a single tertiary care center.MTNR1B基因多态性作为妊娠期糖尿病的危险因素：在单一三级医疗中心进行的病例对照研究
Ann Saudi Med. 2019 Sep-Oct;39(5):309-318. doi: 10.5144/0256-4947.2019.309. Epub 2019 Oct 3.
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Association Between a Melatonin Receptor 1B Genetic Polymorphism and Its Protein Expression in Gestational Diabetes Mellitus.褪黑素受体 1B 基因多态性及其蛋白表达与妊娠期糖尿病的关系。
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The roles of ADIPOQ rs266729 and MTNR1B rs10830963 polymorphisms in patients with gestational diabetes mellitus: A meta-analysis.ADIPOQ rs266729 和 MTNR1B rs10830963 多态性在妊娠期糖尿病患者中的作用：一项荟萃分析。
Gene. 2020 Mar 10;730:144302. doi: 10.1016/j.gene.2019.144302. Epub 2019 Dec 26.
6
Relationship between melatonin receptor 1B (rs10830963 and rs1387153) with gestational diabetes mellitus: a case-control study and meta-analysis.褪黑素受体1B（rs10830963和rs1387153）与妊娠期糖尿病的关系：一项病例对照研究和荟萃分析。
Arch Gynecol Obstet. 2016 Jul;294(1):55-61. doi: 10.1007/s00404-015-3948-y. Epub 2015 Nov 12.
7
Association Study with 77 SNPs Confirms the Robust Role for the rs10830963/G of MTNR1B Variant and Identifies Two Novel Associations in Gestational Diabetes Mellitus Development.对77个单核苷酸多态性的关联研究证实了MTNR1B基因变体rs10830963/G在妊娠期糖尿病发生发展中的重要作用，并发现了两个新的关联。
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[Association between single nucleotide polymorphism of rs4753426 of melatonin receptor 1B gene and gestational diabetes mellitus].褪黑素受体1B基因rs4753426单核苷酸多态性与妊娠期糖尿病的相关性
Zhonghua Fu Chan Ke Za Zhi. 2014 Apr;49(4):276-80.
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Association of Common Genetic Risk Variants With Gestational Diabetes Mellitus and Their Role in GDM Prediction.常见遗传风险变异与妊娠期糖尿病的关联及其在 GDM 预测中的作用。
Front Endocrinol (Lausanne). 2021 Apr 19;12:628582. doi: 10.3389/fendo.2021.628582. eCollection 2021.
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Association between the rs4753426 polymorphism in MTNR1B with fasting plasma glucose level and pancreatic β-cell function in gestational diabetes mellitus.MTNR1B基因rs4753426多态性与妊娠期糖尿病患者空腹血糖水平及胰岛β细胞功能的相关性
Genet Mol Res. 2015 Aug 3;14(3):8778-85. doi: 10.4238/2015.August.3.1.

引用本文的文献

1
Interaction Between Dietary Fiber Intake and rs10830963 Polymorphism on Glycemic Profiles in Young Brazilian Adults.巴西年轻成年人膳食纤维摄入量与rs10830963多态性对血糖谱的相互作用
Genes (Basel). 2025 Apr 27;16(5):497. doi: 10.3390/genes16050497.
2
A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus.一个位于褪黑素受体 1B 的功能性多态性 rs10830963 与妊娠期糖尿病的发病风险相关。
Biosci Rep. 2019 Dec 20;39(12). doi: 10.1042/BSR20190744.
3
MTNR1B genetic polymorphisms as risk factors for gestational diabetes mellitus: a case-control study in a single tertiary care center.
MTNR1B基因多态性作为妊娠期糖尿病的危险因素：在单一三级医疗中心进行的病例对照研究
Ann Saudi Med. 2019 Sep-Oct;39(5):309-318. doi: 10.5144/0256-4947.2019.309. Epub 2019 Oct 3.
4
Melatonin in type 2 diabetes mellitus and obesity.褪黑素与 2 型糖尿病及肥胖。
Nat Rev Endocrinol. 2019 Feb;15(2):105-125. doi: 10.1038/s41574-018-0130-1.
5
From Sea to Shining Sea and the Great Plains to Patagonia: A Review on Current Knowledge of Diabetes Mellitus in Hispanics/Latinos in the US and Latin America.从海洋到海洋，从大平原到巴塔哥尼亚：关于美国和拉丁美洲西班牙裔/拉丁裔糖尿病现状知识的综述
Front Endocrinol (Lausanne). 2017 Nov 10;8:298. doi: 10.3389/fendo.2017.00298. eCollection 2017.
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Prevalence of Gestational Diabetes and Risk of Progression to Type 2 Diabetes: a Global Perspective.妊娠糖尿病的患病率及进展为2型糖尿病的风险：全球视角
Curr Diab Rep. 2016 Jan;16(1):7. doi: 10.1007/s11892-015-0699-x.