Ormiston John, Darremont Olivier, Iwasaki Kiyotaka, Murasato Yoshinobu, Hikichi Yutaka, Webber Bruce, Webster Mark
Mercy Angiography, Auckland, New Zealand.
EuroIntervention. 2015;11 Suppl V:V27-30. doi: 10.4244/EIJV11SVA6.
Bench testing of stents used in bifurcations can provide information on the general properties that influence performance including crossing profile, radial strength, recoil, flexibility and radiopacity. Problems with device delivery can be clarified. Bench testing identified that side branch dilatation caused stent distortion and elucidated correction strategies. Bench testing led to a stent design change adding connectors between hoops to help overcome the clinical problem of longitudinal distortion. Testing on the bench can determine best deployment strategies and showed that a two-step post-dilatation strategy produced the best deployment with "crush" stenting. Scanning electron microscopy showed that withdrawal of a coronary guidewire trapped between a stent (or scaffold) and a mock arterial wall during a provisional side branch stenting strategy caused only mild linear polymer coating damage. Stent fracture can cause adverse clinical events and our repetitive bend test identified the stents most resistant to fracture. Causes of obstruction of the passage of a balloon over a wire through the side of a stent include damage to the catheter tip, complex cell geometry and inadvertent passage of a wire behind a strut. Bench testing plays a major role in validation of computer modelling of bifurcation treatments and flow alterations.
对用于分叉病变的支架进行台架测试,可以提供有关影响其性能的一般特性的信息,包括通过轮廓、径向强度、回缩、柔韧性和射线不透性。器械输送方面的问题可以得到阐明。台架测试发现,边支扩张会导致支架变形,并阐明了纠正策略。台架测试促使支架设计发生改变,即在环之间增加连接件,以帮助克服纵向变形这一临床问题。在台架上进行测试可以确定最佳的置入策略,结果表明,两步后扩张策略在“挤压”支架置入时能产生最佳的置入效果。扫描电子显微镜显示,在临时边支支架置入策略中,冠状动脉导丝被困在支架(或支架平台)与模拟动脉壁之间并被抽出时,只会导致轻度的线性聚合物涂层损伤。支架断裂可导致不良临床事件,我们的重复弯曲试验确定了最抗断裂的支架。球囊通过钢丝穿过支架侧面时通道受阻的原因包括导管尖端受损、复杂的细胞几何形状以及钢丝意外穿过支柱后方。台架测试在分叉病变治疗和血流改变的计算机建模验证中起着重要作用。