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[弥漫性视网膜母细胞瘤——关于一例病例]

[Diffuse retinoblastoma--apropos of a case].

作者信息

Girard B, Brezin A, Gaumond M C, D'Hermies F, Berges O, Cabanis E A, Iba-Zizen M T, Rousselie F

出版信息

Bull Soc Ophtalmol Fr. 1989 Jan;89(1):25-30.

PMID:2598375
Abstract

We report a case of diffuse retinoblastoma in a 6 years old boy. The diagnosis should be suspected in front of the very evocative clinical picture itself. The aspect of the tyndall phenomenon, and of the convex pseudo-hypopyon, with iris pearls and nodules, together with a peripheral, imprecisely limited, retinal mass, non calcified on ultrasonographic examination, are typical. Aqueous paracentesis shows increased levels of Lactic Dehydrogenase (LDH), but most of all the cytologic examination confirms the diagnosis. The only treatment is enucleation. The clinical picture which may simulate uveitis, especially as this particular type of retinoblastoma has a late onset.

摘要

我们报告一例6岁男孩的弥漫性视网膜母细胞瘤。鉴于其极具提示性的临床表现本身,应怀疑该诊断。典型表现为廷德尔现象、伴有虹膜珍珠样结节的凸面假性前房积脓,以及周边部界限不清的视网膜肿物,超声检查显示该肿物无钙化。前房穿刺显示乳酸脱氢酶(LDH)水平升高,但最重要的是细胞学检查确诊了该疾病。唯一的治疗方法是眼球摘除术。这种临床表现可能会模拟葡萄膜炎,尤其是因为这种特殊类型的视网膜母细胞瘤发病较晚。

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