Hong Sang Moon, Kim Tae Wan, Park Kwan Ho
Department of Neurosurgery, Seoul Veterans Hospital, Seoul, Korea.
Korean J Spine. 2012 Mar;9(1):37-40. doi: 10.14245/kjs.2012.9.1.37. Epub 2012 Mar 31.
Multiple myeloma is a B-cell origin tumor characterized by hypercalcemia, osteolytic bony lesions, and pathologic fractures. Back pain is one of the most common presenting symptoms of multiple myeloma and about 60% of patients have vertebral involvement at the time of diagnosis7). Minimally invasive surgeries such as vertebroplasty and kyphoplasty are effective to relieve pain and improve the quality of life when a compression fracture occurs in multiple myeloma patients. We report a case of continuous multiple compression fractures associated with multiple myeloma. We should check for the possibility of pathologic vertebral fractures resulting from multiple myeloma in non-osteoporotic compression fracture patients, and especially in cases of continuous fracture occurring in relatively non-elderly patients, even though a history of trauma may be present.
多发性骨髓瘤是一种起源于B细胞的肿瘤，其特征为高钙血症、溶骨性骨病变和病理性骨折。背痛是多发性骨髓瘤最常见的首发症状之一，约60%的患者在诊断时已有椎体受累7）。当多发性骨髓瘤患者发生压缩性骨折时，椎体成形术和后凸成形术等微创手术可有效缓解疼痛并改善生活质量。我们报告一例与多发性骨髓瘤相关的连续性多发性压缩性骨折病例。对于非骨质疏松性压缩性骨折患者，尤其是相对非老年患者发生连续性骨折的情况，即使存在外伤史，我们也应检查是否存在由多发性骨髓瘤导致的病理性椎体骨折的可能性。
