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包裹性腹膜硬化症治疗后早期肾移植的成功结局

Successful outcome with early renal transplantation following treatment of encapsulating peritoneal sclerosis.

作者信息

Ward Frank, Moran Ann-Marie, Minhas Malik, Watson Alan

机构信息

Department of Nephrology , St. Vincent's University Hospital , Dublin , Ireland.

出版信息

NDT Plus. 2010 Oct;3(5):477-9. doi: 10.1093/ndtplus/sfq122. Epub 2010 Jul 12.

Abstract

Encapsulating peritoneal sclerosis (EPS) is a rare complication of peritoneal dialysis (PD) associated with cocooning of the bowel within a sheath of fibrous tissue causing obstruction. Uncertainty remains regarding the aetiology, pathogenesis and optimal treatment. The current management of EPS is largely based on case reports and small series, and there are limited data regarding outcomes of patients who have undergone renal transplantation following treatment for EPS. We present the case of a 28-year-old man with EPS who was treated surgically followed by anti-fibrotic therapy, with tamoxifen, and 7 months later proceeded to renal transplantation with good outcome.

摘要

包裹性腹膜硬化(EPS)是腹膜透析(PD)的一种罕见并发症,与肠管被包裹在纤维组织鞘内形成“茧状”并导致梗阻有关。关于其病因、发病机制及最佳治疗方法仍存在不确定性。EPS的当前治疗主要基于病例报告和小样本系列研究,关于EPS治疗后接受肾移植患者的预后数据有限。我们报告一例28岁患有EPS的男性患者,该患者接受了手术治疗,随后采用他莫昔芬进行抗纤维化治疗,7个月后进行肾移植,结果良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/097f/4421684/d8d3b2f72ce8/sfq122fig1.jpg

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