Boylan Jennifer Morozink, Ryff Carol D
From the Department of Psychiatry (Boylan), University of Pittsburgh, Pittsburgh, Pennsylvania; and Department of Psychology and Institute on Aging (Ryff), University of Wisconsin-Madison, Madison, Wisconsin.
Psychosom Med. 2015 Jun;77(5):548-58. doi: 10.1097/PSY.0000000000000192.
Psychological well-being predicts favorable cardiovascular outcomes, but less evidence addresses biological mediators underlying these effects. Therefore, associations among well-being and metabolic syndrome (MetSyn) were examined in a national sample.
Survey of Midlife in the US participants (MIDUS; n = 1205) provided survey assessments of hedonic (positive affect, life satisfaction) and eudaimonic well-being (e.g., personal growth and purpose in life) at two waves 9 to 10 years apart. MetSyn components were measured during an overnight clinic visit at Time 2 only. Outcomes included the number of MetSyn risk factors and a binary outcome reflective of MetSyn status.
The unadjusted prevalence of MetSyn was 36.6%. Life satisfaction (B [standard error {SE}] = -0.12 [0.04], p = .005), positive affect (B [SE] = -0.10 [0.04], p = .009), and personal growth (B [SE] = -0.10 [0.04], p = .012) predicted fewer MetSyn components and lower risk of meeting diagnostic criteria in fully adjusted models. Results were unchanged by adjustments for depressive symptoms, and were not moderated by age, sex, race, or socioeconomic status. Life satisfaction (B [SE] = -0.11 [0.05], p = .023) and a eudaimonic well-being composite (B [SE] = -0.11 [0.05], p = .045) also predicted fewer components and lower risk of meeting diagnostic criteria in longitudinal models.
Psychosocial resources, including positive affect, life satisfaction, and personal growth, predicted reduced risk for MetSyn both cross sectionally and longitudinally. Further work should examine consequences of these linkages for cardiovascular outcomes in intervention contexts.
心理健康状况可预测良好的心血管结局,但较少有证据涉及这些影响背后的生物学中介因素。因此,在一个全国性样本中研究了幸福感与代谢综合征(MetSyn)之间的关联。
对美国中年人的调查(MIDUS;n = 1205)在相隔9至10年的两个时间点提供了享乐幸福感(积极情绪、生活满意度)和心理幸福感(如个人成长和生活目的)的调查评估。仅在时间2的夜间门诊就诊期间测量MetSyn的组成部分。结局包括MetSyn危险因素的数量以及反映MetSyn状态的二元结局。
MetSyn的未调整患病率为36.6%。在完全调整模型中,生活满意度(B [标准误{SE}] = -0.12 [0.04],p = .005)、积极情绪(B [SE] = -0.10 [0.04],p = .009)和个人成长(B [SE] = -0.10 [0.04],p = .012)预测MetSyn组成部分较少且达到诊断标准的风险较低。对抑郁症状进行调整后结果不变,且不受年龄、性别、种族或社会经济地位的影响。在纵向模型中,生活满意度(B [SE] = -0.11 [0.05],p = .023)和心理幸福感综合得分(B [SE] = -0.11 [0.05],p = .045)也预测组成部分较少且达到诊断标准的风险较低。
心理社会资源,包括积极情绪、生活满意度和个人成长,在横断面和纵向研究中均预测MetSyn风险降低。进一步的研究应在干预背景下研究这些关联对心血管结局的影响。